Homogeneous Fluid Mixture via Mechanical Mixing

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Solution Overview

Problem

The chemical and pharmaceutical industries face challenges in producing homogeneous liquid mixtures from solid substances, as existing methods require external heating, solvents, and complex temperature control, leading to inefficiencies, contamination, and high costs.

Innovation Solution

A method involving a rotating mixing drum that liquefies and homogenizes solid substances at a temperature lower than their melting point through intensive mixing, eliminating the need for external heat and solvents, and utilizing a vibration mixer to enhance mass transfer and homogeneity.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Productivity

If external heating is used to liquefy solid substances before mixing, then the transition to liquid phase is accelerated, but temperature control complexity increases and local temperature gradients may occur

Engineering Contradiction:
Improvemixing speedVSAvoidtemperature control complexity
Core Design Contradiction:
ProductivityVSDevice complexity

Solution Approach 1:

The patent replaces the thermal field (external heating) with a mechanical field (intensive mixing through rotating drum and agitators). The mechanical energy input through intensive mixing directly facilitates phase transition and homogenization, eliminating the need for complex temperature control systems while maintaining high productivity.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The patent changes the primary process parameter from temperature (thermal energy input) to mechanical energy input (mixing intensity). By controlling mixing speed and intensity rather than temperature, the process achieves phase transition and homogenization without the complexity of temperature control systems.

Inventive Principle:
Principle #35Parameter changes

2Manufacturing precision

If external heating is used to ensure complete liquefaction, then homogeneity is improved, but excessive heating and local temperature differences may occur

Engineering Contradiction:
Improvemixture homogeneityVSAvoidexcessive heating
Core Design Contradiction:
Manufacturing precisionVSObject-affected harmful factors

Solution Approach 1:

The patent replaces thermal energy input with mechanical energy input through intensive mixing. The mechanical action of the rotating drum and agitators provides uniform energy distribution throughout the mixture, achieving complete homogenization without the risk of excessive heating or local temperature gradients that plague thermal processes.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The intensive mixing process is self-regulating in terms of energy distribution. The mechanical energy is automatically distributed uniformly throughout the mixture by the mixing action itself, eliminating the need for external temperature control systems and preventing localized overheating.

Inventive Principle:
Principle #25Self-service

3Manufacturing precision

If solvents are added to facilitate mixing of solids, then mixing results are improved, but additional time and costs are incurred for solvent removal

Engineering Contradiction:
Improvemixing homogeneityVSAvoidsolvent removal time
Core Design Contradiction:
Manufacturing precisionVSLoss of time

Solution Approach 1:

The patent extracts and eliminates the solvent step from the traditional mixing process. By using intensive mechanical mixing alone, the process achieves complete homogenization of solid substances without requiring any solvent, thereby eliminating the time-consuming solvent removal step entirely.

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The intensive mixing system is self-sufficient and does not require external agents like solvents. The mechanical energy input directly facilitates phase transition and homogenization, making the process inherently solvent-free and eliminating all associated time and cost overheads.

Inventive Principle:
Principle #25Self-service

4Productivity

If intensive mixing is used to achieve homogeneity, then mixing time is reduced, but contamination from surface abrasion may increase

Engineering Contradiction:
Improvemixing speedVSAvoidcontamination from abrasion
Core Design Contradiction:
ProductivityVSObject-generated harmful factors

Solution Approach 1:

The patent uses a disposable or easily replaceable liner inside the mixing drum that contacts the mixture. This liner absorbs the wear and contamination issues, protecting the main mixing drum from abrasion while allowing intensive mixing to proceed at high speeds without contamination concerns.

Inventive Principle:
Principle #27Cheap short-living objects (Disposable)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This method produces a homogeneous liquid mixture quickly and cost-effectively, reducing contamination risks and operational complexity, while ensuring high purity and efficiency in mixing large quantities.

Implementation Method 1

Through suitable intensive movement of the mixing container, the mass transfer at the phase boundaries of the substances with one another is intensified, which results in a lowering of the melting point compared to the individual substances and thus the transition to the liquid phase

Methodology Applied
Scientific EffectMass transfer: Diffusion

Implementation Method 2

Furthermore, the wall friction that occurs causes the liquid phase to be homogenized

Methodology Applied
Scientific EffectFriction: Friction

Data Source

PatentEP2033707B1Method for manufacturing a homogenous fluid mixture
Publication Date: 2011.03.09 MERCK PATENT GMBH
  • EP2033707B1 patent drawingFigure 1
  • EP2033707B1 patent drawing
  • EP2033707B1 patent drawing

AI summary

Preparation of a homogeneous liquid mixture from at least two organic substances, comprises liquefying at least one of the substances, which are in solid form at room temperature and a substance to be mixed in a temperature, which is less than the melt temperature of the existing substance, by intensive mixing, and homogenizing the obtained mixture.