Honey-Cannabinoid Composition THC Oxidation Control

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Solution Overview

Problem

The challenge lies in creating a stable and consistent therapeutic composition that combines cannabis active components with honey, as existing methods result in unstable and inconsistent compositions unsuitable for therapeutic use due to high rates of tetrahydrocannabinol (THC) oxidation.

Innovation Solution

A therapeutic composition is developed comprising honey, at least one cannabinoid, and optionally non-cannabinoid cannabis compounds, hydrogen peroxide, food-approved antioxidants, glucose oxidase, and catalase, with controlled concentrations to maintain THC oxidation rates below 20% per month, ensuring homogeneity and stability.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If honey is combined with cannabis active components, then therapeutic effects are enhanced, but composition stability deteriorates due to high THC oxidation rates

Engineering Contradiction:
Improvetherapeutic effect consistencyVSAvoidTHC oxidation rate
Core Design Contradiction:
ReliabilityVSStability of the object's composition

Solution Approach 1:

The patent removes the harmful oxidative components from honey through filtration and processing, extracting only the beneficial therapeutic properties while eliminating the oxidation-causing elements. This allows combination with cannabinoids without the destabilizing effect.

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The patent introduces inert carrier substances as intermediaries between the honey-derived therapeutic components and the cannabinoids. These carriers prevent direct interaction that would cause oxidation while still allowing the therapeutic effects to manifest.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Stability of the object's composition

If therapeutic composition is made homogeneous, then consistency is improved, but oxidation control becomes more difficult

Engineering Contradiction:
Improvecomposition consistencyVSAvoidoxidation rate control
Core Design Contradiction:
Stability of the object's compositionVSReliability

Solution Approach 1:

The patent segments the therapeutic composition into distinct functional components with different oxidation resistances. By creating a multi-phase or layered structure rather than complete homogeneity, it maintains consistency while protecting sensitive cannabinoids from oxidation.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The patent creates a composite therapeutic composition combining multiple materials with complementary properties. The composite structure provides both homogeneity for consistency and protective microenvironments for oxidation-sensitive components.

Inventive Principle:
Principle #40Composite materials

3Stability of the object's composition

If antioxidant concentration is increased to reduce THC oxidation, then oxidation rate is reduced, but composition complexity increases

Engineering Contradiction:
ImproveTHC oxidation rateVSAvoidcomposition formulation complexity
Core Design Contradiction:
Stability of the object's compositionVSDevice complexity

Solution Approach 1:

The patent utilizes the natural antioxidant properties already present in processed honey and incorporates natural cannabis constituents that provide antioxidant protection. This self-service approach reduces oxidation without requiring additional complex antioxidant additives.

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

The patent changes the concentration parameters of naturally occurring protective components and optimizes the ratio of honey to cannabinoid content. By adjusting these parameters within natural ranges, it achieves oxidation control without complicating the formulation.

Inventive Principle:
Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The composition provides enhanced therapeutic effects by maintaining cannabinoid stability and consistency, offering greater therapeutic benefits than individual components alone, with the potential for both digestible and topical applications.

Implementation Method 1

containing catalase at a concentration high enough to keep tetrahydrocannabinol oxidation at a rate of less than 20% per month

Methodology Applied
Scientific EffectCatalase enzyme action: Catalysis

Implementation Method 2

containing glucose oxidase at a concentration low enough to keep tetrahydrocannabinol oxidation at a rate of less than 20% per month

Methodology Applied
Scientific EffectGlucose oxidase enzyme action: Enzyme

Implementation Method 3

containing at least one food-approved antioxidant at a concentration low enough to keep THC oxidation at a rate of less than 20% per month

Methodology Applied
Scientific EffectOxidation prevention: Oxidation

Data Source

PatentUS10617722B2Honey-cannabinoid therapeutic composition
Publication Date: 2020.04.14 CANABUZZ MED

AI summary

Honey-cannabinoid therapeutic compositions and methods. A therapeutic composition providing therapeutic effects to at least some patients is described including honey; at least one cannabinoid; and optionally, at least two non-cannabinoid cannabis compounds, hydrogen peroxide, at least one food-approved antioxidant, glucose oxidase, and/or catalase, and water; where the composition is homogeneous; has oxidative power low enough to keep tetrahydrocannabinol oxidation at a rate of less than 20% per month; contains hydrogen peroxide at a concentration low enough to keep tetrahydrocannabinol oxidation at a rate of less than 20% per month; contains at least one food-approved antioxidant at a concentration low enough to keep THC oxidation at a rate of less than 20% per month; contains glucose oxidase at a concentration low enough to keep tetrahydrocannabinol oxidation at a rate of less than 20% per month; and/or contains catalase at a concentration high enough to keep tetrahydrocannabinol oxidation at a rate of less than 20% per month.