Nutritional Supplement for OCD Lesion Prevention in Horses

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Solution Overview

Problem

Osteochondritis dissecans (OCD) lesions in young horses are a significant economic problem due to genetic predisposition and nutritional imbalances, leading to joint damage and pain, with existing treatments being costly and ineffective in preventing the condition.

Innovation Solution

A novel dietary supplement formulated with specific nutrients such as ascorbic acid, Thiamine, Omega-3 fatty acids, tryptophan, Glucosamine hydrochloride, and chondroitin sulfate, designed to mitigate metabolic defects associated with OCD development, administered to horses to inhibit or prevent the condition.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If surgical correction is used to treat OCD lesions, then the condition can be corrected, but the treatment is expensive and affected horses bring lower prices

Engineering Contradiction:
ImproveOCD lesion correctionVSAvoidtreatment cost
Core Design Contradiction:
ReliabilityVSQuantity of substance

Solution Approach 1:

The patent applies preliminary action by administering the nutritional supplement to horses before OCD lesions develop or in early stages, based on metabolic profiling that identifies horses at risk. This preventive approach avoids the need for expensive surgical correction later, directly resolving the contradiction between effective treatment and high cost.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The patent converts the harmful metabolic imbalances that predispose horses to OCD into a beneficial preventive strategy. By identifying and correcting specific metabolic deficiencies through targeted nutritional supplementation, the harmful metabolic state is transformed into an opportunity for early intervention, preventing expensive surgical treatment.

Inventive Principle:
Principle #22Blessing in disguise (Convert harm into benefit)

2Reliability

If conventional nutritional approaches are used, then general nutrition is provided, but they do not effectively prevent OCD development

Engineering Contradiction:
ImproveOCD prevention efficacyVSAvoidformula complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The patent applies local quality by providing targeted nutritional supplementation based on each horse's specific metabolic profile. Rather than using a generic nutritional approach, the formula is customized to address specific metabolic deficiencies identified through NMR spectroscopy, thereby effectively preventing OCD without requiring overly complex individualized formulations for every possible deficiency.

Inventive Principle:
Principle #3Local quality

Solution Approach 2:

The patent changes the parameters of nutritional supplementation from general, non-specific nutrition to targeted nutrition based on metabolic parameters identified through NMR spectroscopy. By adjusting nutritional parameters according to specific metabolic profiles, the patent achieves effective OCD prevention with a manageable formula complexity.

Inventive Principle:
Principle #35Parameter changes

3Measurement precision

If NMR Spectroscopy and Metabonomics are used to identify metabolic defects, then precise metabolic profiling is achieved, but the complexity of analysis increases

Engineering Contradiction:
Improvemetabolic profiling accuracyVSAvoidanalysis complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The patent performs preliminary metabolic profiling using NMR spectroscopy to identify horses at risk for OCD before lesions develop. This early detection allows for preventive nutritional intervention, and the metabolic profiles are stored and compared against reference data, reducing the need for complex real-time analysis during treatment.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The patent uses NMR spectroscopy as an intermediary tool to translate complex metabolic information into simple, actionable nutritional recommendations. The metabolic profiling serves as a mediator between the complex internal metabolic state and the straightforward nutritional intervention, making the overall system manageable despite the complexity of the underlying biology.

Inventive Principle:
Principle #24Intermediary (Mediator)

Data Source

PatentUS10143219B2Nutritional supplement/feed formula and methods of use thereof to reduce development of Osteochondrosis Dissecans (OCD) lesions
Publication Date: 2018.12.04 RUTGERS THE STATE UNIV
  • US10143219B2 patent drawing
  • US10143219B2 patent drawing
  • US10143219B2 patent drawing

AI summary

A novel dietary supplement and nutritional aid and methods for the manufacture and administration of the same are disclosed for the inhibition of OCD in afflicted animals, particularly horses. The present invention relates generally to a feed composition and methods of use thereof for reducing the development of Osteochondrosis Dissecans (OCD) lesions in predisposed young animals, particularly horses. More specifically the invention provides a nutritional formula that targets the metabolic deficiencies identified as being correlated with development of OCD.