Heart Rate Variability Monitoring for Hypercapnia Detection

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Solution Overview

Problem

Current methods for detecting hypercapnia are invasive, time-intensive, and not suitable for real-time, continuous monitoring, posing a risk due to the potential for delayed detection of elevated carbon dioxide levels in blood.

Innovation Solution

A portable system that monitors heart rate variability using ECG electrodes integrated into a wearable patch, with a data collection and processing device capable of real-time analysis and alert generation, providing non-invasive detection of physiological stress indicative of hypercapnia.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If arterial blood gas panel is used to detect hypercapnia, then measurement precision is improved, but device complexity and ease of operation worsen due to invasive procedure requiring specialized equipment

Engineering Contradiction:
Improveblood CO2 levels detection accuracyVSAvoidspecialized equipment requirement
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The patent replaces the mechanical/invasive blood sampling system with an optical/electrical monitoring system using ECG electrodes and heart rate variability analysis. This substitution eliminates the need for specialized blood analysis equipment while providing continuous non-invasive monitoring of hypercapnia conditions.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The patent introduces heart rate variability as an intermediary parameter to indirectly measure blood CO2 levels. Instead of directly measuring CO2 in blood, the system uses HRV changes as a mediator that correlates with hypercapnia, simplifying the detection mechanism while maintaining measurement precision.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Measurement precision

If arterial blood gas panel is used to detect hypercapnia, then measurement precision is improved, but loss of time increases due to time-intensive procedure

Engineering Contradiction:
Improveblood CO2 levels detection accuracyVSAvoiddetection time
Core Design Contradiction:
Measurement precisionVSLoss of time

Solution Approach 1:

The patent implements continuous monitoring of heart rate variability over time, allowing for real-time detection of hypercapnia onset. This continuous action replaces the discrete, time-intensive blood gas panel procedure, enabling immediate detection without repeated invasive sampling while maintaining measurement precision through ongoing data collection and analysis.

Inventive Principle:
Principle #20Continuity of useful action

3Ease of operation

If simple non-invasive monitoring method is used, then ease of operation is improved, but measurement precision worsens compared to arterial blood gas panel

Engineering Contradiction:
Improvemonitoring simplicityVSAvoidhypercapnia detection accuracy
Core Design Contradiction:
Ease of operationVSMeasurement precision

Solution Approach 1:

The patent employs feedback mechanisms where heart rate variability data is continuously analyzed and compared against threshold values to detect hypercapnia. The system provides real-time feedback through alerts when abnormal patterns are detected, maintaining measurement precision through automated analysis while preserving ease of operation by eliminating manual blood sampling and analysis.

Inventive Principle:
Principle #23Feedback

4Reliability

If arterial blood gas panel is used, then reliability is improved for detecting hypercapnia, but device complexity and ease of operation worsen

Engineering Contradiction:
Improvehypercapnia detection reliabilityVSAvoidprocedure complexity
Core Design Contradiction:
ReliabilityVSEase of operation

Solution Approach 1:

The patent enables the monitoring system to automatically perform data collection, analysis, and alert generation without requiring specialized medical personnel or equipment operation. The device serves itself by continuously monitoring ECG signals and autonomously detecting hypercapnia conditions, thereby maintaining reliability while dramatically improving ease of operation compared to manual blood gas panel procedures.

Inventive Principle:
Principle #25Self-service

Data Source

PatentUS11800988B1Systems and methods for monitoring heart rate variability
Publication Date: 2023.10.31 UNIV OF SOUTH FLORIDA
  • US11800988B1 patent drawing
  • US11800988B1 patent drawing
  • US11800988B1 patent drawing

AI summary

In one embodiment, a system for monitoring heart rate variability including an electrode configured to be placed against a user’s chest and generate heart beat data and a data collection and processing device that receives the heart beat data from the electrode, the data collection and processing device being configured to execute a heart rate variability program configured to continually determine the user’s heart rate variability in real time based upon the heart beat data and to determine whether or not the user is in physiological distress based upon the determined heart rate variability.