Humic Acid Clay Mycotoxin Binder for Feed

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Solution Overview

Problem

Current methods for detoxifying mycotoxin-contaminated grain on a large scale are not cost-effective and often impair nutrient utilization, with existing adsorbents failing to effectively bind multiple mycotoxins and causing adverse effects in animal feeds.

Innovation Solution

Development of mycotoxin binders comprising 10% to 90% humic substances with 45% or more humic acid, combined with 10% to 90% clay materials, which exhibit high in vitro binding efficiency and minimal desorption, effectively adsorbing zearalenone and other mycotoxins in the gastrointestinal tract.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If existing adsorbents are used to bind mycotoxins, then mycotoxin binding capacity is improved, but nutrient utilization is impaired

Engineering Contradiction:
Improvemycotoxin binding capacityVSAvoidnutrient utilization
Core Design Contradiction:
ReliabilityVSProductivity

Solution Approach 1:

The invention combines humic substances with clay materials to create a composite binder that selectively binds mycotoxins while allowing nutrients to pass through. This composite structure enables differentiation between mycotoxin binding and nutrient absorption, resolving the contradiction between effective mycotoxin removal and maintained nutrient utilization.

Inventive Principle:
Principle #40Composite materials

2Reliability

If conventional detoxification methods are applied on a large scale, then mycotoxin removal is improved, but cost-effectiveness deteriorates

Engineering Contradiction:
Improvemycotoxin removal efficiencyVSAvoidcost-effectiveness
Core Design Contradiction:
ReliabilityVSEase of manufacture

Solution Approach 1:

The invention employs naturally occurring humic substances that are abundant, inexpensive, and effective at binding mycotoxins. These materials can be sourced from natural deposits and processed into cost-effective feed additives, making large-scale detoxification economically viable while maintaining high removal efficiency.

Inventive Principle:
Principle #27Cheap short-living objects (Disposable)

3Ease of manufacture

If single-material binders are used, then manufacturing simplicity is improved, but binding effectiveness against multiple mycotoxins deteriorates

Engineering Contradiction:
Improvemanufacturing simplicityVSAvoidbinding effectiveness against multiple mycotoxins
Core Design Contradiction:
Ease of manufactureVSAdaptability or versatility

Solution Approach 1:

The invention creates a composite binder combining humic substances with clay materials, where each component contributes different binding properties. This composite structure enables the binder to effectively adsorb multiple types of mycotoxins simultaneously, overcoming the limitation of single-material binders while remaining manufacturable through straightforward mixing processes.

Inventive Principle:
Principle #40Composite materials

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The humic acid-based mycotoxin binders demonstrate an in vitro binding efficiency of at least 80% and minimal desorption, significantly reducing the adverse effects of mycotoxins on animal health and productivity, thereby improving feed quality and safety.

Implementation Method 1

The humic acid-based mycotoxin binders demonstrate an in vitro binding efficiency of at least 80% and minimal desorption, significantly reducing the adverse effects of mycotoxins on animal health and productivity

Methodology Applied
Scientific EffectAdsorption: Adsorption

Data Source

PatentEP2571384B1Mycotoxin binder
Publication Date: 2019.10.23 KEMIN INDUSTRIES INC
  • EP2571384B1 patent drawingFigure 1~2
  • EP2571384B1 patent drawingFigure 3~4
  • EP2571384B1 patent drawingFigure 5

AI summary

A mycotoxin binder is disclosed characterized by 45% or more humic acid, maximum solubility of 20% at pH between 1.5 and 7.0, and an in vitro mycotoxin binding efficiency of at least 80% and preferably 90% with adsorption of at least 85% at pH 3.0 and desorption less than 10% at pH 6.8.