HYA Triglyceride Derivative for Liquid State and Flavor
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Solution Overview
Problem
10-hydroxy-cis-12-octadecenoic acid (HYA) has superior physiological functions but is solid at ambient temperature and has an acrid flavor, making it difficult to ingest and handle effectively.
Innovation Solution
A novel triglyceride is developed where at least one fatty acid forms an ester bond with the hydroxy group of glycerol, specifically using 10-hydroxy-cis-12-octadecenoic acid or its optical isomer, which is liquid at ambient temperature and has a good flavor, allowing for easy ingestion and handling.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If HYA is used directly, then physiological functions are improved, but handling and ingestion become difficult due to solid state and acrid flavor
Solution Approach 1:
The patent changes the physical state parameter of HYA from solid to liquid by converting it into a triglyceride derivative form. This parameter change resolves the contradiction by maintaining the physiological functionality of HYA while eliminating the handling difficulties associated with its solid state and acrid flavor.
Solution Approach 2:
The patent creates a composite structure by incorporating HYA into a triglyceride molecule, where HYA forms an ester bond with glycerol. This composite approach allows HYA to be delivered in a form that combines the beneficial physiological effects of HYA with the favorable handling properties of liquid triglycerides.
2Ease of operation
If HYA is converted to triglyceride derivative, then handling and ingestion become easy, but the direct physiological effect may be reduced
Solution Approach 1:
The triglyceride derivative acts as an intermediary carrier that delivers HYA to the body. The ester bond in the triglyceride structure allows for enzymatic hydrolysis in the digestive system, releasing free HYA that can then exert its physiological effects. This intermediary approach resolves the contradiction by facilitating easy ingestion while ensuring physiological functionality is restored through in vivo hydrolysis.
Solution Approach 2:
The patent performs preliminary action by pre-converting HYA into a triglyceride derivative form that is easier to handle and ingest. This preliminary transformation does not permanently alter HYA's functionality, as the ester bond can be broken down in the body to release the active HYA molecule when needed.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The triglyceride derivative is liquid at ambient temperature, has a pleasant flavor, and upon ingestion, the ester bond is hydrolyzed by lipase, releasing HYA, thereby exerting its superior physiological functions such as improving lipid metabolism and enhancing intestinal immunity.
Implementation Method 1
the ester bond is hydrolyzed by lipase, releasing HYA
Data Source
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AI summary
The present invention provides a novel HYA derivative having superior physiological functions intrinsic to HYA and permitting easy ingestion and easy handling, and use thereof. The present invention relates to a triglyceride in which at least one fatty acid forming an ester bond with a hydroxy group of glycerol is 10-hydroxy-cis-12-octadecenoic acid, or an optical isomer thereof, and a composition (edible fat or oil, food, medicament, cosmetic etc.) containing same.