Hyaluronic Acid Injection for Nerve Decompression and Healing

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Solution Overview

Problem

Current treatments for neurological dysfunction caused by pinched nerves, such as carpal tunnel syndrome, often fall short in providing comprehensive relief, especially when combined with surgical methods like neurolysis, as they do not adequately address the underlying nerve compression issues.

Innovation Solution

A composition comprising hyaluronic acid, administered topically or via injection during surgical procedures like neurolysis, to alleviate neurological dysfunction by reducing pressure on compressed nerves, utilizing a 2% non-cross-linked hyaluronic acid solution with mannitol for enhanced stability and slower flow properties to support nerve enclosure.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If surgical methods like neurolysis are used to treat pinched nerves, then nerve decompression is achieved, but wound healing and recurrence prevention remain insufficient

Engineering Contradiction:
Improvetreatment effectivenessVSAvoidwound healing
Core Design Contradiction:
ReliabilityVSEase of repair

Solution Approach 1:

The patent combines surgical neurolysis with hyaluronic acid injection into a single integrated treatment protocol. The hyaluronic acid is administered during the surgical procedure, merging the decompression function with the healing function in one treatment session, thereby improving both nerve decompression and wound healing outcomes simultaneously

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

Hyaluronic acid serves as a medicinal intermediary substance that mediates between the surgical intervention and the healing process. It provides a protective environment for the nerve, reduces inflammation, and promotes tissue repair, bridging the gap between surgical decompression and effective wound healing

Inventive Principle:
Principle #24Intermediary (Mediator)

2Ease of operation

If conventional treatments are used for pinched nerves, then some symptom relief is provided, but comprehensive nerve protection and recurrence prevention are inadequate

Engineering Contradiction:
Improvesymptom reliefVSAvoidnerve protection
Core Design Contradiction:
Ease of operationVSReliability

Solution Approach 1:

The patent uses a composite approach by combining the mechanical decompression effect of neurolysis with the biochemical protective effects of hyaluronic acid. This composite treatment provides both immediate symptom relief through decompression and long-term nerve protection through the pharmacological actions of hyaluronic acid, including anti-inflammatory and neuroprotective properties

Inventive Principle:
Principle #40Composite materials

Data Source

PatentEP4085905B1Hyaluronic acid for use in preventing or treating neurological dysfunction of nerves or nerve cells
Publication Date: 2024.02.21 CHEMEDICA

AI summary

The present invention relates to a composition comprising hyaluronic acid for use in preventing or treating neurological dysfunction of at least one nerve or nerve cell.