Hybrid Corn CH010381 CMS Breeding

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Solution Overview

Problem

The challenge in corn breeding is to develop hybrid varieties that combine desirable traits such as high yield, disease resistance, and uniformity, while maintaining genetic stability and avoiding self-pollination.

Innovation Solution

The development of the hybrid corn variety CH010381, which includes a cytoplasmic or nuclear factor for male sterility or self-incompatibility, along with genetic modifications that confer traits like herbicide resistance, insect resistance, and disease resistance, is achieved through advanced breeding techniques and genetic transformation.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If corn plants are allowed to self-pollinate, then genetic stability is maintained, but hybrid vigor and desirable trait combination are lost

Engineering Contradiction:
Improvegenetic stabilityVSAvoidhybrid vigor
Core Design Contradiction:
ReliabilityVSProductivity

Solution Approach 1:

The patent removes the male reproductive capability from the female parent plant through cytoplasmic male sterility (CMS), extracting the self-pollination function entirely. This ensures the female parent cannot self-pollinate while maintaining genetic stability, and forces cross-pollination to achieve hybrid vigor in the offspring.

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The patent introduces a male sterility system as an intermediary mechanism that controls pollination. The CMS cytoplasm acts as a mediator that prevents self-pollination while allowing controlled cross-pollination, enabling hybrid seed production without manual emasculation.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Productivity

If manual emasculation is performed to prevent self-pollination, then cross-pollination is achieved, but labor cost and time consumption increase

Engineering Contradiction:
Improvecross-pollination efficiencyVSAvoidbreeding process complexity
Core Design Contradiction:
ProductivityVSDevice complexity

Solution Approach 1:

The patent employs cytoplasmic male sterility to enable the plant to self-regulate pollination prevention. The female parent automatically prevents self-pollination through its CMS cytoplasm, eliminating the need for manual emasculation and reducing labor costs and process complexity.

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

The male sterility system serves as an intermediary that automates the emasculation function. Instead of manual intervention, the CMS cytoplasm mediates the prevention of self-pollination, simplifying the breeding process while maintaining cross-pollination efficiency.

Inventive Principle:
Principle #24Intermediary (Mediator)

3Productivity

If multiple desirable traits are combined in a single variety, then agricultural productivity improves, but genetic complexity and breeding difficulty increase

Engineering Contradiction:
Improveagricultural productivityVSAvoidbreeding program complexity
Core Design Contradiction:
ProductivityVSDevice complexity

Solution Approach 1:

The patent combines multiple desirable traits (disease resistance, yield improvement, stress tolerance) into a single hybrid variety, creating a multi-functional plant that addresses multiple agricultural challenges simultaneously. The hybrid CH010381 integrates traits from both parental inbreds to achieve broad-spectrum benefits.

Inventive Principle:
Principle #6Universality (Multi-functionality)

Solution Approach 2:

The patent creates a composite genetic structure by combining two homozygous inbred lines with different trait profiles. The hybrid variety functions as a composite of parental genomes, where each parent contributes specific desirable traits that complement each other in the offspring.

Inventive Principle:
Principle #40Composite materials

4Stability of the object's composition

If homozygous inbred plants are developed through self-pollination, then genetic uniformity is achieved, but loss of heterozygosity reduces vigor

Engineering Contradiction:
Improvegenetic uniformityVSAvoidplant vigor
Core Design Contradiction:
Stability of the object's compositionVSProductivity

Solution Approach 1:

The patent performs preliminary self-pollination to develop homozygous inbred parental lines with stable, uniform genetics. These inbreds serve as standardized building blocks that, when crossed, produce vigorous F1 hybrids with heterosis, thus preparing the genetic material in advance to resolve the vigor uniformity trade-off.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The patent divides the breeding process into separate stages: first developing homozygous inbred parents through self-pollination, then crossing them to produce hybrid offspring. This segmentation allows genetic uniformity to be achieved in the parental generation while heterosis is realized in the hybrid generation.

Inventive Principle:
Principle #1Segmentation

Data Source

PatentUS12268158B2Plants and seeds of hybrid corn variety CH010381
Publication Date: 2025.04.08 MONSANTO TECHNOLOGY LLC

AI summary

According to the invention, there is provided seed and plants of the hybrid corn variety designated CH010381. The invention thus relates to the plants, seeds and tissue cultures of the variety CH010381, and to methods for producing a corn plant produced by crossing a corn plant of variety CH010381 with itself or with another corn plant, such as a plant of another variety. The invention further relates to genetic complements of plants of variety CH010381.