Hybrid Corn CH010416 Cytoplasmic Male Sterility Breeding

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Solution Overview

Problem

The challenge in corn breeding is to develop hybrid varieties that combine desirable traits such as high yield, disease resistance, and uniformity, while also addressing issues like self-pollination and the need for stable inbred parental plants.

Innovation Solution

The development of the hybrid corn variety CH010416, which includes genetic modifications and cytoplasmically-inherited traits to confer characteristics like male sterility, herbicide resistance, and disease resistance, while also being capable of producing seed with specific agronomic and nutritional traits.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Stability of the object's composition

If self-pollination is prevented through male sterility mechanisms, then hybrid uniformity is improved, but breeding complexity increases

Engineering Contradiction:
Improvehybrid uniformityVSAvoidbreeding complexity
Core Design Contradiction:
Stability of the object's compositionVSDevice complexity

Solution Approach 1:

The patent employs cytoplasmic male sterility (CMS) where the female parent's cytoplasm inherently prevents self-pollination without requiring external intervention. The sterility is self-regulated through the interaction between cytoplasmic genes and nuclear restorer genes, automatically ensuring hybrid uniformity while simplifying the breeding process compared to manual emasculation methods.

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

Instead of using traditional methods where the male parent determines pollination control, the patent inverts the approach by using the female parent's cytoplasm to control male fertility. This inversion through CMS systems allows the female to actively prevent self-pollination, thereby improving hybrid uniformity while reducing breeding complexity.

Inventive Principle:
Principle #13The other way round (Inversion)

2Adaptability or versatility

If multiple desirable traits are combined in a single hybrid variety, then agronomic quality is improved, but breeding difficulty increases

Engineering Contradiction:
Improveagronomic qualityVSAvoidbreeding difficulty
Core Design Contradiction:
Adaptability or versatilityVSDevice complexity

Solution Approach 1:

The patent merges multiple desirable traits including disease resistance, yield improvement, and stress tolerance into a single hybrid variety through systematic crossing programs. By combining inbred lines with complementary traits and using CMS-based hybridization, the patent achieves multi-trait integration while managing breeding complexity through structured parental selection and evaluation protocols.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The developed hybrid variety serves multiple functions simultaneously: it provides high yield, disease resistance, stress tolerance, and uniform performance across different environments. This multi-functionality is achieved through careful selection of parental inbreds that contribute different desirable traits, which are then combined and stabilized in the F1 hybrid generation.

Inventive Principle:
Principle #6Universality (Multi-functionality)

3Stability of the object's composition

If inbred parental plants are developed through repeated selfing, then genetic uniformity is improved, but time to maturity increases

Engineering Contradiction:
Improvegenetic uniformityVSAvoidtime to maturity
Core Design Contradiction:
Stability of the object's compositionVSLoss of time

Solution Approach 1:

The patent develops inbred parental lines through repeated selfing and selection before the actual hybridization program begins. This preliminary development of genetically uniform inbreds establishes a stable foundation for subsequent hybrid production, allowing the time-consuming uniformity achievement to occur in advance rather than during the hybrid breeding process itself.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

Once uniform inbred lines are developed, they serve as stable parental copies that can be repeatedly used to produce hybrid seed. The genetically uniform inbreds act as standardized sources that can be propagated and used across multiple hybridization cycles, reducing the need to re-develop uniformity from scratch for each new hybrid variety.

Inventive Principle:
Principle #26Copying

Data Source

PatentUS12317832B2Plants and seeds of hybrid corn variety CH010416
Publication Date: 2025.06.03 MONSANTO TECHNOLOGY LLC

AI summary

According to the invention, there is provided seed and plants of the hybrid corn variety designated CH010416. The invention thus relates to the plants, seeds and tissue cultures of the variety CH010416, and to methods for producing a corn plant produced by crossing a corn plant of variety CH010416 with itself or with another corn plant, such as a plant of another variety. The invention further relates to genetic complements of plants of variety CH010416.