Hybrid Corn CH010443 CMS Restorer Genetics

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Solution Overview

Problem

The challenge in corn breeding is to develop hybrid varieties that combine desirable traits such as high yield, disease resistance, and uniformity, while maintaining genetic stability and avoiding self-pollination.

Innovation Solution

The development of the hybrid corn variety CH010443, which includes a cytoplasmic or nuclear factor conferring male sterility or self-incompatibility to prevent self-pollination, along with genetic modifications that introduce traits like herbicide resistance, insect resistance, and altered metabolism.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Adaptability or versatility

If self-pollination is allowed in corn breeding, then genetic diversity is maintained, but uniformity of hybrid progeny deteriorates

Engineering Contradiction:
Improvegenetic diversityVSAvoiduniformity of hybrid progeny
Core Design Contradiction:
Adaptability or versatilityVSManufacturing precision

Solution Approach 1:

The patent extracts and removes the male reproductive capability from the female parent plant through cytoplasmic male sterility (CMS). By introducing specific mitochondrial genes (cms-M, cms-E, or cms-T) into the female parent, the system eliminates self-pollination capability, ensuring that only cross-pollination occurs and uniform hybrid progeny are produced while maintaining controlled genetic diversity through selective breeding programs.

Inventive Principle:
Principle #2Taking out (Extraction)

2Manufacturing precision

If male sterility is introduced to prevent self-pollination, then uniformity of hybrid progeny is improved, but device complexity increases

Engineering Contradiction:
Improveuniformity of hybrid progenyVSAvoidgenetic system complexity
Core Design Contradiction:
Manufacturing precisionVSDevice complexity

Solution Approach 1:

The patent employs self-service through restorer genes (Rf1, Rf2, Rf3) that automatically restore male fertility in the F1 hybrid progeny. The restorer genes are dominantly inherited and automatically compensate for the male sterility introduced in the parental generation, eliminating the need for manual intervention to restore fertility while maintaining uniformity in hybrid production.

Inventive Principle:
Principle #25Self-service

3Stability of the object's composition

If inbreeding is used to develop homozygous lines, then genetic stability is improved, but productivity decreases due to inbreeding depression

Engineering Contradiction:
Improvegenetic stabilityVSAvoidyield
Core Design Contradiction:
Stability of the object's compositionVSProductivity

Solution Approach 1:

The patent merges the benefits of inbreeding (genetic stability and uniformity) with the benefits of hybridization (heterosis and high yield). By using CMS to force cross-pollination between two homozygous inbred lines, the system produces F1 hybrids that exhibit both the genetic uniformity of inbred lines and the high productivity of hybrid plants, effectively combining previously opposing breeding goals.

Inventive Principle:
Principle #5Merging (Combining)

Data Source

PatentUS20250185576A1Plants and seeds of hybrid corn variety ch010443
Publication Date: 2025.06.12 MONSANTO TECHNOLOGY LLC

AI summary

According to the disclosure, there is provided seed and plants of the hybrid com variety designated CH010443. The disclosure thus relates to the plants, seeds, and tissue cultures of the variety CH010443, and to methods for producing a corn plant produced by crossing a corn plant of variety CH010443 with itself or with another corn plant, such as a plant of another variety. The disclosure further relates to genetic complements of plants of variety CH010443.