Hybrid Corn CH010987 Breeding via Male Sterility

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Solution Overview

Problem

Current corn breeding techniques face challenges in developing hybrid varieties that combine desirable traits such as high yield, disease resistance, and uniformity, while maintaining genetic stability and avoiding self-pollination, which limits the introduction of new genetic modifications and traits.

Innovation Solution

The development of the hybrid corn variety CH010987, which incorporates a cytoplasmic or nuclear factor for male sterility and genetic modifications conferring traits like herbicide resistance, disease resistance, and altered metabolism, using techniques like backcrossing and genome editing to introduce specific alleles and transgenes, ensuring cross-pollination and maintaining genetic stability.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Productivity

If self-pollination is prevented through male sterility mechanisms, then cross-pollination and hybrid variety development are improved, but the complexity of breeding programs increases due to the need for maintaining sterility systems

Engineering Contradiction:
Improvehybrid variety developmentVSAvoidbreeding program complexity
Core Design Contradiction:
ProductivityVSDevice complexity

Solution Approach 1:

The patent employs cytoplasmic male sterility (CMS) as an intermediary mechanism to prevent self-pollination. The CMS trait acts as a mediator that naturally blocks pollen production in female parent plants, eliminating the need for manual emasculation and simplifying hybrid seed production while maintaining controlled cross-pollination

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The patent extracts and utilizes specific cytoplasmic factors (cms1, cms2, cms3) that confer male sterility. By isolating and deploying these specific sterility-inducing cytoplasmic elements, the breeding program achieves automatic self-pollination prevention without requiring complex mechanical or chemical intervention systems

Inventive Principle:
Principle #2Taking out (Extraction)

2Adaptability or versatility

If genetic modifications are introduced to confer desirable traits, then agronomic quality and resistance are improved, but genetic stability may be compromised

Engineering Contradiction:
Improveagronomic qualityVSAvoidgenetic stability
Core Design Contradiction:
Adaptability or versatilityVSStability of the object's composition

Solution Approach 1:

The patent performs preliminary genetic modifications in the inbred parent lines before hybridization. Desirable traits such as herbicide resistance (e.g., imidazolinone, sulfonylurea, glyphosate resistance) and disease resistance are pre-introduced and stabilized in the parental inbreds through multiple generations of selection, ensuring these traits are fixed and stable before combining them in the hybrid

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The patent merges multiple stabilized genetic traits from different inbred parents into a single hybrid variety. The hybrid combines resistance traits, yield characteristics, and agronomic qualities from both parents, achieving superior adaptability while maintaining genetic stability through the uniformity of the F1 hybrid generation

Inventive Principle:
Principle #5Merging (Combining)

3Manufacturing precision

If uniformity in germination and growth is achieved through inbred lines, then phenotypic consistency is improved, but the introduction of new traits becomes more difficult

Engineering Contradiction:
Improvephenotypic uniformityVSAvoidtrait introduction
Core Design Contradiction:
Manufacturing precisionVSAdaptability or versatility

Solution Approach 1:

The patent segments the breeding process into distinct phases: developing uniform inbred parent lines with specific stabilized traits, then combining them through controlled cross-pollination. This segmentation allows each parent to be optimized for uniformity while the hybrid combination introduces new trait combinations, resolving the conflict between uniformity and trait diversity

Inventive Principle:
Principle #1Segmentation

Data Source

PatentUS12048284B2Plants and seeds of hybrid corn variety CH010987
Publication Date: 2024.07.30 MONSANTO TECHNOLOGY LLC

AI summary

According to the invention, there is provided seed and plants of the hybrid corn variety designated CH010987. The invention thus relates to the plants, seeds and tissue cultures of the variety CH010987, and to methods for producing a corn plant produced by crossing a corn plant of variety CH010987 with itself or with another corn plant, such as a plant of another variety. The invention further relates to genetic complements of plants of variety CH010987.