Hybrid Corn CH011010 Breeding via Genetic Male Sterility

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Solution Overview

Problem

Current corn breeding techniques face challenges in developing hybrid varieties that combine desirable traits such as high yield, disease resistance, and uniformity, while maintaining genetic stability and avoiding self-pollination, which limits the efficiency of trait introduction and hybrid seed production.

Innovation Solution

The development of the hybrid corn variety CH011010, which incorporates genetic modifications and cytoplasmic male sterility traits to prevent self-pollination, along with tissue culture methods for regenerating plants with specific physiological and morphological characteristics, and the use of genome editing techniques to introduce heritable traits like herbicide resistance and disease resistance.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Productivity

If self-pollination is allowed in corn breeding, then genetic stability is maintained, but hybrid seed production efficiency is reduced due to uncontrollable pollination

Engineering Contradiction:
Improvehybrid seed production efficiencyVSAvoidgenetic stability
Core Design Contradiction:
ProductivityVSStability of the object's composition

Solution Approach 1:

The patent applies preliminary action by pre-modifying the pollination control mechanism through genetic engineering. Male sterile lines are developed in advance with controlled pollination capabilities, and pollination control mechanisms (such as genetic male sterility or conditional sterility systems) are established before hybrid seed production begins. This allows breeders to start with plants that have predetermined pollination behaviors, eliminating the need for manual emasculation and ensuring consistent cross-pollination outcomes.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The patent uses genetic mechanisms as intermediaries to control pollination. Genetic male sterility genes or conditional sterility systems act as mediators between the male and female plants, enabling controlled cross-pollination without direct human intervention. These genetic intermediaries regulate pollen production and fertilization processes, ensuring that only desired crosses occur while maintaining genetic stability through controlled inheritance patterns.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Adaptability or versatility

If traditional breeding methods are used to combine multiple desirable traits, then genetic diversity is increased, but the complexity of breeding programs increases and development time is extended

Engineering Contradiction:
Improvetrait combination capabilityVSAvoidbreeding program complexity
Core Design Contradiction:
Adaptability or versatilityVSDevice complexity

Solution Approach 1:

The patent applies merging by combining multiple desirable traits into single parent lines through systematic breeding programs. Inbred lines are developed that already contain combinations of desired traits (such as disease resistance, yield components, and stress tolerance), which then serve as ready-to-use parental materials. This merging of traits into consolidated parental lines simplifies the hybrid development process, as breeders can directly cross pre-characterized lines rather than managing multiple separate trait introduction programs.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The patent utilizes parameter changes by modifying key breeding parameters such as generation time, selection intensity, and cross-compatibility controls. Molecular markers and genomic selection tools enable faster trait identification and fixation, reducing the number of generations required to develop stable lines. Conditional male sterility systems and other genetic parameters are adjusted to optimize cross-pollination efficiency and simplify hybrid seed production logistics.

Inventive Principle:
Principle #35Parameter changes

3Reliability

If manual emasculation is performed to prevent self-pollination, then cross-pollination control is improved, but labor requirements and production costs increase

Engineering Contradiction:
Improvecross-pollination controlVSAvoidhybrid seed production ease
Core Design Contradiction:
ReliabilityVSEase of manufacture

Solution Approach 1:

The patent applies self-service by enabling plants to automatically control their own pollination behavior through genetic mechanisms. Male sterile lines are engineered to self-regulate pollen production based on environmental cues or genetic triggers, eliminating the need for manual emasculation. The plants themselves perform the pollination control function that previously required human labor, through mechanisms such as temperature-sensitive sterility, photoperiod-controlled fertility, or chemically-induced sterility that can be activated without physical intervention.

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

The patent replaces the mechanical system of manual emasculation with biological/genetic systems. Instead of physically removing anthers or preventing pollen discharge through mechanical means, the invention uses genetic male sterility genes, hormonal control mechanisms, or environmentally-responsive sterility systems to regulate pollination. This substitution of mechanical operations with biological control mechanisms dramatically reduces labor requirements while maintaining or improving pollination control reliability.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Data Source

PatentUS11856910B2Plants and seeds of hybrid corn variety CH011010
Publication Date: 2024.01.02 MONSANTO TECHNOLOGY LLC

AI summary

According to the invention, there is provided seed and plants of the hybrid corn variety designated CH011010. The invention thus relates to the plants, seeds and tissue cultures of the variety CH011010, and to methods for producing a corn plant produced by crossing a corn plant of variety CH011010 with itself or with another corn plant, such as a plant of another variety. The invention further relates to genetic complements of plants of variety CH011010.