Hybrid Corn CH011092 Cytoplasmic Male Sterility

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Solution Overview

Problem

Current corn breeding techniques face challenges in developing hybrid varieties that combine desirable traits such as high yield, disease resistance, and uniformity, while maintaining genetic stability and avoiding self-pollination, which limits the efficiency of hybrid seed production.

Innovation Solution

The development of the hybrid corn variety CH011092, which incorporates genetic modifications and cytoplasmic male sterility traits to prevent self-pollination, along with a process for crossing parent plants to produce seeds with enhanced characteristics like herbicide resistance, disease resistance, and improved agronomic traits, using techniques like genome editing and tissue culture regeneration.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Productivity

If traditional self-pollination breeding methods are used, then genetic stability is maintained, but hybrid seed production efficiency is limited due to self-pollination

Engineering Contradiction:
Improvehybrid seed production efficiencyVSAvoidgenetic stability
Core Design Contradiction:
ProductivityVSStability of the object's composition

Solution Approach 1:

The patent applies preliminary anti-action by introducing cytoplasmic male sterility (CMS) into the female parent before crossing. This prevents self-pollination in advance by rendering the female parent male-sterile through cytoplasmic factors, ensuring that only cross-pollination can occur. The CMS trait is maintained through specific cytoplasmic-genic interactions that prevent pollen formation, thereby eliminating the need for manual emasculation and ensuring high hybrid seed production efficiency while maintaining genetic purity.

Inventive Principle:
Principle #9Preliminary anti-action

Solution Approach 2:

The patent uses cytoplasmic male sterility as an intermediary mechanism to control pollination. The cytoplasmic factors act as mediators between the female parent's genetic composition and its reproductive capability, allowing breeders to achieve controlled cross-pollination without direct manipulation. This intermediary system enables efficient hybrid seed production by automatically preventing self-pollination through cytoplasmic-nuclear interactions that result in male sterility.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Productivity

If cytoplasmic male sterility is introduced to prevent self-pollination, then hybrid seed production efficiency improves, but genetic complexity increases

Engineering Contradiction:
Improvehybrid seed production efficiencyVSAvoidgenetic complexity
Core Design Contradiction:
ProductivityVSDevice complexity

Solution Approach 1:

The patent extracts the male fertility function from the female parent by introducing cytoplasmic male sterility. This separation allows the female parent to contribute only female reproductive cells (eggs) to the hybrid, while male fertility is provided exclusively by the male parent. By taking out the male fertility function from the female side, the system simplifies the breeding process and enables efficient hybrid seed production without the complexity of managing both parents' fertility status.

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The patent segments the reproductive functions into distinct cytoplasmic and nuclear components. The cytoplasmic male sterility is maintained through specific cytoplasmic-genic interactions where cytoplasmic factors (such as mitochondrial genes) interact with nuclear restorer genes. This segmentation allows independent management of sterility and fertility traits, simplifying the overall genetic system while improving hybrid seed production efficiency.

Inventive Principle:
Principle #1Segmentation

3Reliability

If inbred plants are developed through multiple generations of selfing, then uniformity is achieved, but time to maturity increases

Engineering Contradiction:
ImproveuniformityVSAvoidtime to maturity
Core Design Contradiction:
ReliabilityVSLoss of time

Solution Approach 1:

The patent applies preliminary action by developing homozygous inbred lines through multiple generations of selfing before the actual hybridization step. This preliminary development of uniform parental lines ensures that when crossing occurs, the F1 hybrids exhibit consistent and uniform traits. The time investment in creating stable inbred parents beforehand allows for rapid production of uniform hybrid seeds in subsequent generations, achieving reliability without excessive delays in the main production cycle.

Inventive Principle:
Principle #10Preliminary action

Data Source

PatentUS11425875B2Plants and seeds of hybrid corn variety CH011092
Publication Date: 2022.08.30 MONSANTO TECHNOLOGY LLC

AI summary

According to the invention, there is provided seed and plants of the hybrid corn variety designated CH011092. The invention thus relates to the plants, seeds and tissue cultures of the variety CH011092, and to methods for producing a corn plant produced by crossing a corn plant of variety CH011092 with itself or with another corn plant, such as a plant of another variety. The invention further relates to genetic complements of plants of variety CH011092.