Hybrid Corn CH011107 Cytoplasmic Male Sterility Seed Production

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Solution Overview

Problem

Current corn breeding techniques face challenges in developing hybrid varieties that combine desirable traits such as high yield, disease resistance, and uniformity, while maintaining genetic stability and avoiding self-pollination, which limits the efficiency of hybrid seed production.

Innovation Solution

The development of the hybrid corn variety CH011107, which incorporates genetic modifications and cytoplasmic male sterility to prevent self-pollination, along with specific traits like herbicide resistance and disease resistance, achieved through genetic transformation and backcrossing techniques, allowing for controlled cross-pollination and stable hybrid seed production.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Productivity

If self-pollination is allowed in corn breeding, then genetic diversity is maintained, but hybrid seed production efficiency decreases due to uncontrollable pollination

Engineering Contradiction:
Improvehybrid seed production efficiencyVSAvoidpollination control
Core Design Contradiction:
ProductivityVSReliability

Solution Approach 1:

The patent removes the male reproductive capability from the female parent by inducing male sterility, thereby extracting the self-pollination possibility from the breeding system. This ensures that the female parent can only receive pollen from the male parent, achieving complete pollination control while maintaining high hybrid seed production efficiency

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The patent introduces a male sterility factor as an intermediary mechanism that mediates between the need for genetic diversity and pollination control. This sterility factor acts as a biological mediator that prevents self-pollination while allowing controlled cross-pollination, resolving the contradiction between reliability and productivity

Inventive Principle:
Principle #24Intermediary (Mediator)

2Adaptability or versatility

If multiple desirable traits are combined in hybrid corn, then agronomic quality improves, but breeding complexity increases

Engineering Contradiction:
Improveagronomic qualityVSAvoidbreeding program complexity
Core Design Contradiction:
Adaptability or versatilityVSDevice complexity

Solution Approach 1:

The patent combines multiple desirable traits (high yield, disease resistance, stress tolerance) into a single hybrid variety by systematically crossing inbred lines that each contribute specific traits. The male sterility system facilitates this merging by enabling efficient hybridization without the complexity of manual emasculation, thus improving agronomic quality while managing breeding program complexity

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The patent performs preliminary development of homozygous inbred lines with specific traits before combining them in hybrid crosses. This preliminary action allows traits to be selected and stabilized in parent lines, reducing the complexity of managing multiple traits simultaneously in the breeding program while ensuring high agronomic quality in the final hybrid

Inventive Principle:
Principle #10Preliminary action

3Stability of the object's composition

If inbred lines are developed through extensive selfing, then genetic uniformity improves, but inbre depression increases

Engineering Contradiction:
Improvegenetic uniformityVSAvoidplant vigor
Core Design Contradiction:
Stability of the object's compositionVSReliability

Solution Approach 1:

The patent creates a uniform population of hybrid plants that copy the optimal heterozygous genotype from the F1 cross. This copying approach allows the hybrid to inherit the genetic uniformity of inbred parents while avoiding inbreed depression through heterosis, achieving both genetic stability and plant vigor

Inventive Principle:
Principle #26Copying

Solution Approach 2:

The patent converts the harmful effect of inbreed depression into a benefit by using highly inbred parental lines to produce vigorous hybrid offspring. The extensive selfing that causes inbreed depression in parents actually ensures genetic uniformity and purity in the parental lines, which when crossed produce uniform, vigorous hybrids that express heterosis, thus turning the harm of inbreeding into the benefit of hybrid vigor

Inventive Principle:
Principle #22Blessing in disguise (Convert harm into benefit)

Data Source

PatentUS11425874B2Plants and seeds of hybrid corn variety CH011107
Publication Date: 2022.08.30 MONSANTO TECHNOLOGY LLC

AI summary

According to the invention, there is provided seed and plants of the hybrid corn variety designated CH011107. The invention thus relates to the plants, seeds and tissue cultures of the variety CH011107, and to methods for producing a corn plant produced by crossing a corn plant of variety CH011107 with itself or with another corn plant, such as a plant of another variety. The invention further relates to genetic complements of plants of variety CH011107.