Hybrid Corn CH011128 Cytoplasmic Male Sterility Breeding

Resolve Bottlenecks,
Find Innovative Solutions
Generate Solutions

Solution Overview

Problem

Current corn breeding techniques face challenges in developing hybrid varieties that combine desirable traits such as high yield, disease resistance, and uniformity, while maintaining genetic stability and avoiding self-pollination, which limits the efficiency of trait introduction and hybrid seed production.

Innovation Solution

The development of the hybrid corn variety CH011128, which incorporates genetic modifications for traits like male sterility, herbicide resistance, and disease resistance, utilizing cytoplasmic male sterility and genetic transformation techniques, along with specific breeding processes to prevent self-pollination and enhance cross-pollination, allowing for the introduction of desirable traits and stable hybrid seed production.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Adaptability or versatility

If traditional breeding methods are used to develop hybrid corn varieties, then genetic diversity and trait combination are improved, but self-pollination occurs which reduces hybrid seed production efficiency

Engineering Contradiction:
Improvetrait combinationVSAvoidhybrid seed production efficiency
Core Design Contradiction:
Adaptability or versatilityVSProductivity

Solution Approach 1:

The patent extracts the male fertility function from the hybrid corn plant by introducing cytoplasmic male sterility (CMS) genes. This removes the ability of the hybrid plant to produce functional pollen, preventing self-pollination and ensuring that only cross-pollinated seeds are produced, thereby improving hybrid seed production efficiency while maintaining genetic diversity.

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The patent uses CMS restorer genes as intermediaries to control pollination. These restorer genes, when introduced into the hybrid, can restore male fertility in specific controlled scenarios while maintaining sterility in the standard hybrid configuration. This intermediary mechanism allows precise control over self-pollination versus cross-pollination outcomes.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Productivity

If cytoplasmic male sterility is introduced to prevent self-pollination, then hybrid seed production efficiency is improved, but genetic stability may be compromised

Engineering Contradiction:
Improvehybrid seed production efficiencyVSAvoidgenetic stability
Core Design Contradiction:
ProductivityVSStability of the object's composition

Solution Approach 1:

The patent changes the cytoplasmic parameter by introducing specific CMS cytoplasm types (such as T-cytoplasm, S-cytoplasm, or C-cytoplasm) that confer male sterility. These cytoplasmic changes are stable and heritable, allowing the hybrid to maintain sterility across generations while preserving nuclear genetic stability. The cytoplasmic modification does not affect the stability of nuclear genes responsible for other important traits.

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent segments the genetic control of fertility into cytoplasmic (sterility) and nuclear (restoration) components. This segmentation allows independent control and stabilization of each component, ensuring that cytoplasmic male sterility is maintained for hybrid seed production while nuclear genetic stability is preserved for trait expression and inheritance.

Inventive Principle:
Principle #1Segmentation

3Adaptability or versatility

If multiple desirable traits are combined in a single hybrid variety, then agronomic quality is improved, but breeding complexity increases

Engineering Contradiction:
Improveagronomic qualityVSAvoidbreeding complexity
Core Design Contradiction:
Adaptability or versatilityVSDevice complexity

Solution Approach 1:

The patent creates a universal hybrid corn variety that simultaneously expresses multiple desirable traits including disease resistance, herbicide tolerance, improved yield, and cytoplasmic male sterility. By integrating these multiple functions into a single hybrid variety through coordinated parental selection and CMS introduction, the breeding process achieves multi-functionality without proportionally increasing complexity, as the CMS mechanism provides a unified control point for all these traits.

Inventive Principle:
Principle #6Universality (Multi-functionality)

Data Source

PatentUS11419288B2Plants and seeds of hybrid corn variety CH011128
Publication Date: 2022.08.23 MONSANTO TECHNOLOGY LLC

AI summary

According to the invention, there is provided seed and plants of the hybrid corn variety designated CH011128. The invention thus relates to the plants, seeds and tissue cultures of the variety CH011128, and to methods for producing a corn plant produced by crossing a corn plant of variety CH011128 with itself or with another corn plant, such as a plant of another variety. The invention further relates to genetic complements of plants of variety CH011128.