Hybrid Corn CH011190 Breeding via Male Sterility Segmentation

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Solution Overview

Problem

Current corn breeding techniques face challenges in developing hybrid varieties that combine desirable traits such as high yield, disease resistance, and uniformity, while maintaining genetic stability and avoiding self-pollination, which limits the introduction of new genetic modifications and traits.

Innovation Solution

The development of the hybrid corn variety CH011190, which incorporates a cytoplasmic or nuclear factor for male sterility and genetic modifications conferring traits like herbicide resistance, disease resistance, and altered metabolism, using techniques like genome editing and transgenic integration, along with tissue culture methods for regenerating plants with specific characteristics.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Stability of the object's composition

If traditional self-pollination breeding methods are used, then genetic uniformity is achieved, but genetic diversity and introduction of new traits are limited

Engineering Contradiction:
Improvegenetic uniformityVSAvoidgenetic diversity
Core Design Contradiction:
Stability of the object's compositionVSAdaptability or versatility

Solution Approach 1:

The patent segments the breeding process into distinct phases: using male-sterile lines to prevent self-pollination and ensure cross-pollination, then separately introducing genetic modifications through transformation techniques. This segmentation allows achieving both genetic uniformity in the hybrid population and introduction of new traits through controlled genetic modification.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The patent uses male-sterility as an intermediary mechanism to control pollination. By introducing a male-sterile factor (cytoplasmic or nuclear) as a mediator, the system prevents self-pollination while facilitating cross-pollination, thereby achieving genetic uniformity through controlled mating while allowing introduction of new genetic material.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Adaptability or versatility

If cross-pollination is used to increase genetic diversity, then new traits can be introduced, but genetic stability and uniformity are reduced

Engineering Contradiction:
Improvegenetic diversityVSAvoidgenetic uniformity
Core Design Contradiction:
Adaptability or versatilityVSStability of the object's composition

Solution Approach 1:

The patent applies preliminary action by first establishing male-sterility in the parental lines before crossing. This preliminary genetic modification ensures that cross-pollination occurs uniformly across the population, producing genetically uniform F1 hybrids with desired new traits, thereby achieving both genetic diversity and uniformity.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The patent changes the pollination parameter from natural self-pollination to controlled cross-pollination by introducing male-sterility. This parameter change enables uniform cross-pollination across the population, producing genetically uniform hybrids while introducing new genetic material, thus resolving the contradiction between uniformity and diversity.

Inventive Principle:
Principle #35Parameter changes

3Ease of operation

If male sterility factors are introduced to prevent self-pollination, then controlled cross-pollination is achieved, but device complexity increases

Engineering Contradiction:
Improvecontrolled pollinationVSAvoidgenetic system complexity
Core Design Contradiction:
Ease of operationVSDevice complexity

Solution Approach 1:

The patent applies self-service by using self-incompatibility mechanisms inherent in the plant's genetic system. The male-sterile lines automatically prevent self-pollination through genetic control, eliminating the need for manual emasculation or complex mechanical pollination control devices, thus achieving controlled cross-pollination without proportionally increasing system complexity.

Inventive Principle:
Principle #25Self-service

4Adaptability or versatility

If genetic modifications are introduced to confer desired traits, then adaptability and versatility improve, but genetic stability may be compromised

Engineering Contradiction:
Improvetrait diversityVSAvoidgenetic stability
Core Design Contradiction:
Adaptability or versatilityVSStability of the object's composition

Solution Approach 1:

The patent extracts the male-sterility trait separately from other genetic modifications. By isolating the male-sterile factor in parental lines and then introducing additional genetic modifications through transformation in a controlled manner, the system maintains genetic stability of the core hybrid genome while allowing introduction of specific new traits, thus resolving the contradiction between adaptability and stability.

Inventive Principle:
Principle #2Taking out (Extraction)

Data Source

PatentUS11997973B2Plants and seeds of hybrid corn variety CH011190
Publication Date: 2024.06.04 MONSANTO TECHNOLOGY LLC

AI summary

According to the invention, there is provided seed and plants of the hybrid corn variety designated CH011190. The invention thus relates to the plants, seeds and tissue cultures of the variety CH011190, and to methods for producing a corn plant produced by crossing a corn plant of variety CH011190 with itself or with another corn plant, such as a plant of another variety. The invention further relates to genetic complements of plants of variety CH011190.