Hybrid Corn CH011202 Breeding via Male Sterility and Segmentation

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Solution Overview

Problem

Current corn breeding techniques face challenges in developing hybrid varieties that combine desirable traits such as high yield, disease resistance, and uniformity, while maintaining genetic stability and avoiding self-pollination, which limits the introduction of new genetic modifications and cytoplasmically inherited traits.

Innovation Solution

The development of the hybrid corn variety CH011202, which incorporates genetic modifications and cytoplasmically inherited traits like male sterility, herbicide resistance, and disease resistance, using techniques like genome editing and backcrossing, along with tissue culture methods to regenerate plants with specific physiological and morphological characteristics.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Stability of the object's composition

If traditional self-pollination breeding methods are used, then genetic stability is maintained, but genetic diversity and hybrid vigor are limited

Engineering Contradiction:
Improvegenetic stabilityVSAvoidgenetic diversity
Core Design Contradiction:
Stability of the object's compositionVSAdaptability or versatility

Solution Approach 1:

The breeding program segments the population into distinct inbred lines through controlled self-pollination, creating genetically stable parental lines that can be systematically crossed to generate hybrid progeny with both stability and diversity

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

Genetically stable inbred lines are merged through cross-pollination to create hybrid corn varieties that exhibit heterosis, combining the benefits of genetic stability from pure lines with the adaptability and vigor of hybrid genetics

Inventive Principle:
Principle #5Merging (Combining)

2Adaptability or versatility

If cross-pollination is used to develop hybrid varieties, then genetic diversity and hybrid vigor are improved, but maintaining genetic stability and preventing self-pollination becomes more difficult

Engineering Contradiction:
Improvehybrid vigorVSAvoidgenetic stability
Core Design Contradiction:
Adaptability or versatilityVSStability of the object's composition

Solution Approach 1:

Male sterility systems act as intermediaries to prevent self-pollination and ensure cross-pollination occurs, using cytoplasmic or nuclear factors that control fertility to maintain hybrid integrity and genetic stability

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The fertility parameter of the plant is changed through male sterility systems, transforming the ability to self-pollinate into an inability, thereby forcing cross-pollination and maintaining hybrid variety stability

Inventive Principle:
Principle #35Parameter changes

3Stability of the object's composition

If conventional breeding methods are used, then existing traits are maintained, but introduction of new genetic modifications and cytoplasmically inherited traits is limited

Engineering Contradiction:
Improvetrait consistencyVSAvoidintroduction of new traits
Core Design Contradiction:
Stability of the object's compositionVSAdaptability or versatility

Solution Approach 1:

Desirable traits such as disease resistance, herbicide tolerance, and improved yield characteristics are pre-introduced into parental inbred lines through genetic modification or conventional breeding before hybridization, ensuring trait consistency in the hybrid variety

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The hybrid variety is created as a composite genetic system combining nuclear genes from both parents with cytoplasmic elements from the maternal line, allowing integration of both conventional and genetically modified traits in a single stable variety

Inventive Principle:
Principle #40Composite materials

Data Source

PatentUS12167712B2Plants and seeds of hybrid corn variety CH011202
Publication Date: 2024.12.17 MONSANTO TECHNOLOGY LLC

AI summary

According to the invention, there is provided seed and plants of the hybrid corn variety designated CH011202. The invention thus relates to the plants, seeds and tissue cultures of the variety CH011202, and to methods for producing a corn plant produced by crossing a corn plant of variety CH011202 with itself or with another corn plant, such as a plant of another variety. The invention further relates to genetic complements of plants of variety CH011202.