Hybrid Corn CH405760 Controlled Pollination via CMS

Resolve Bottlenecks,
Find Innovative Solutions
Generate Solutions

Solution Overview

Problem

Current corn breeding techniques face challenges in developing hybrid varieties that combine desirable traits such as high yield, disease resistance, and uniformity, while maintaining genetic stability and avoiding self-pollination, which limits the introduction of new genetic modifications and traits.

Innovation Solution

The development of the hybrid corn variety CH405760, which incorporates genetic modifications for traits like male sterility, herbicide resistance, and disease resistance, utilizing cytoplasmic and nuclear factors, and genetic locus conversions through backcrossing and genetic transformation techniques, allowing for controlled pollination and stable trait introduction.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Adaptability or versatility

If traditional self-pollination breeding methods are used, then genetic stability and uniformity are maintained, but the introduction of new genetic modifications and traits is limited

Engineering Contradiction:
Improveintroduction of new genetic modificationsVSAvoidgenetic stability
Core Design Contradiction:
Adaptability or versatilityVSStability of the object's composition

Solution Approach 1:

The patent applies preliminary action by creating male-sterile inbred lines before hybrid production, which are then crossed with maintainer lines to produce hybrid seeds. This preliminary preparation of sterile lines enables subsequent controlled cross-pollination while maintaining genetic stability through the maintainer line system.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The patent uses an intermediary system involving maintainer lines and cytoplasmic male sterility factors. The maintainer line acts as an intermediary that produces pollen to fertilize male-sterile lines, enabling controlled cross-pollination without self-pollination while preserving genetic stability through the specific cytoplasmic-nuclear interaction system.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Productivity

If cross-pollination is used to combine desirable traits, then yield and diversity are improved, but control over pollination and self-pollination prevention becomes difficult

Engineering Contradiction:
ImproveyieldVSAvoidcontrol over pollination
Core Design Contradiction:
ProductivityVSEase of operation

Solution Approach 1:

The patent applies self-service by using cytoplasmic male sterility factors that automatically prevent self-pollination without requiring external intervention. The male-sterile inbred lines inherently cannot self-fertilize, and the system self-regulates through the interaction between sterile lines and maintainer lines, eliminating the need for manual emasculation or pollination control.

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

The patent replaces mechanical pollination control systems (such as manual emasculation, bagging, or isolation barriers) with a biological mechanism based on cytoplasmic male sterility. This substitution uses genetic-cytoplasmic interaction to achieve controlled cross-pollination, simplifying operation and improving reliability.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

3Stability of the object's composition

If inbred lines are developed through multiple generations of selfing, then homozygosity and uniformity are achieved, but the process is time-consuming and complex

Engineering Contradiction:
ImprovehomozygosityVSAvoidbreeding cycle time
Core Design Contradiction:
Stability of the object's compositionVSLoss of time

Solution Approach 1:

The patent applies segmentation by dividing the breeding process into distinct functional components: male-sterile inbred lines, maintainer lines, and hybrid production. This segmentation allows parallel development of sterile lines and maintainer lines, reducing the sequential time required compared to traditional single-line development approaches.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The patent utilizes parameter changes in the cytoplasmic-nuclear genetic interaction system. By introducing specific cytoplasmic male sterility factors and restorer genes, the system changes the pollination parameter from self-pollination to controlled cross-pollination, enabling faster hybrid production while maintaining the homozygosity achieved through inbreeding.

Inventive Principle:
Principle #35Parameter changes

Data Source

PatentUS20190364831A1Plants and seeds of hybrid corn variety ch405760
Publication Date: 2019.12.05 MONSANTO TECHNOLOGY LLC

AI summary

According to the invention, there is provided seed and plants of the hybrid corn variety designated CH405760. The invention thus relates to the plants, seeds and tissue cultures of the variety CH405760, and to methods for producing a corn plant produced by crossing a corn plant of variety CH405760 with itself or with another corn plant, such as a plant of another variety. The invention further relates to genetic complements of plants of variety CH405760.