Hybrid Corn Variety CH010546 With CMS for Uniform Breeding

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Solution Overview

Problem

Existing corn breeding techniques struggle to develop hybrids with uniformity and desirable traits such as increased yield, resistance to pests and diseases, and improved agronomic qualities, while maintaining genetic stability and commercial viability.

Innovation Solution

The development of the hybrid corn variety CH010546, which incorporates cytoplasmic and nuclear factors for male sterility, genetic modifications for traits like herbicide resistance, and a method for controlled cross-pollination using emasculation and bagging techniques, along with genetic editing tools like CRISPR-Cas systems, to enhance genetic diversity and stability.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If traditional breeding methods are used to develop hybrid corn varieties, then uniformity and desirable traits can be achieved, but the process requires extensive selection and cross-breeding over multiple generations, increasing time and resource requirements

Engineering Contradiction:
Improveuniformity of hybrid populationVSAvoidtime required for breeding
Core Design Contradiction:
ReliabilityVSLoss of time

Solution Approach 1:

The patent employs cytoplasmic male sterility (CMS) systems where the female parent is pre-programmed to be sterile, eliminating the need for manual detasseling and ensuring uniform hybrid production from the first generation. This preliminary genetic setup achieves uniformity without extensive multi-generational selection.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The patent replaces mechanical detasseling operations with genetic control mechanisms. By using CMS cytoplasm in the female parent, the mechanical removal of tassels is substituted with a genetic system that naturally prevents self-pollination, reducing labor and time requirements while maintaining uniformity.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

2Adaptability or versatility

If extensive selection and cross-breeding are performed to develop stable inbred plants, then desirable traits such as disease resistance and yield can be incorporated, but the complexity of the breeding program increases

Engineering Contradiction:
Improvedesirable traits in hybridVSAvoidbreeding program complexity
Core Design Contradiction:
Adaptability or versatilityVSDevice complexity

Solution Approach 1:

The patent segments the breeding program into distinct parental lines with specific predetermined traits. Each parent is developed independently with focused characteristics (e.g., one parent for disease resistance, another for yield), and the hybrid combines these segmented traits without requiring complex multi-trait selection in a single population.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The patent uses CMS cytoplasm as an intermediary mechanism that facilitates hybrid production without requiring complex breeding operations. The CMS system acts as a mediator that ensures cross-pollination occurs while the parents maintain their individual trait profiles, simplifying the overall breeding program structure.

Inventive Principle:
Principle #24Intermediary (Mediator)

3Reliability

If manual detasseling is performed to prevent self-pollination and ensure hybrid uniformity, then cross-pollination can be controlled, but labor requirements and operational complexity increase

Engineering Contradiction:
Improveprevention of self-pollinationVSAvoidoperational simplicity
Core Design Contradiction:
ReliabilityVSEase of operation

Solution Approach 1:

The patent replaces manual detasseling operations with a genetic system (cytoplasmic male sterility) that automatically prevents self-pollination. The CMS cytoplasm in the female parent naturally inhibits pollen production, eliminating the need for mechanical intervention while maintaining reliable prevention of self-pollination.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The patent implements a self-service system where the female parent plant itself prevents self-pollination through its CMS cytoplasm. The plant's own genetic makeup ensures cross-pollination occurs without requiring external manual intervention, simplifying operations while maintaining reliability.

Inventive Principle:
Principle #25Self-service

Data Source

PatentUS12610906B2Plants and seeds of hybrid corn variety CH010546
Publication Date: 2026.04.28 MONSANTO TECHNOLOGY LLC

AI summary

According to the disclosure, there is provided seed and plants of the hybrid corn variety designated CH010546. The disclosure thus relates to the plants, seeds, and tissue cultures of the variety CH010546, and to methods for producing a corn plant produced by crossing a corn plant of variety CH010546 with itself or with another corn plant, such as a plant of another variety. The disclosure further relates to genetic complements of plants of variety CH010546.