Hybrid Corn Seed Production with Female Height Differentiation

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Solution Overview

Problem

The existing methods for hybrid corn seed production are inefficient and costly, particularly in terms of female inbred corn plant yield, which is a critical factor in commercial corn seed profitability.

Innovation Solution

The method involves fertilizing or crossing female inbred corn plants with male inbred corn plants, where the female plants have a mutant allele in the GA20 oxidase or Brachytic2 (Br2) locus, resulting in a shorter stature and producing hybrid corn seeds, utilizing antisense RNA sequences or genome modifications to achieve a 2.5% height reduction.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Productivity

If conventional methods are used for hybrid corn seed production, then production can proceed with standard plant heights, but female inbred corn plant yield and production efficiency remain suboptimal

Engineering Contradiction:
Improvefemale inbred corn plant yieldVSAvoidproduction cost
Core Design Contradiction:
ProductivityVSEase of manufacture

Solution Approach 1:

The patent applies parameter changes by modifying the plant height parameter through genetic manipulation. Female inbred corn plants are engineered to be at least 2.5% shorter than male plants through mutations in GA20 oxidase or Brachytic2 loci, creating a height differential that improves pollination efficiency and seed yield while reducing production costs

Inventive Principle:
Principle #35Parameter changes

2Productivity

If female and male corn plants have similar heights, then planting is simpler, but pollination efficiency and seed production are reduced

Engineering Contradiction:
Improveseed production efficiencyVSAvoidplant height differential
Core Design Contradiction:
ProductivityVSLength of moving object

Solution Approach 1:

The patent implements asymmetry by creating a deliberate height difference between female and male corn plants. Female plants are genetically modified to be shorter than male plants, creating an asymmetric structure that enhances pollination efficiency and seed production while maintaining simplicity in planting operations

Inventive Principle:
Principle #4Asymmetry

3Productivity

If standard corn plant genetics are used, then breeding is straightforward, but hybrid seed yield and profitability are limited

Engineering Contradiction:
Improvehybrid corn seed yieldVSAvoidgenetic modification complexity
Core Design Contradiction:
ProductivityVSDevice complexity

Solution Approach 1:

The patent changes genetic parameters by introducing mutations in specific loci (GA20 oxidase or Brachytic2) that control plant height. This genetic parameter modification creates the desired height differential while improving hybrid seed yield and profitability, balancing genetic complexity with production benefits

Inventive Principle:
Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This approach enhances the yield and efficiency of hybrid corn seed production by optimizing the height and genetic traits of female inbred corn plants, thereby improving profitability and productivity.

Implementation Method 1

the DNA segment encodes an antisense RNA sequence that is at least 70% complementary to at least 20 consecutive nucleotides of one or more of SEQ ID NOs: 182-184 and 186-188

Methodology Applied
Scientific EffectAntisense RNA binding:

Data Source

PatentUS12527250B2Methods for improved hybrid corn seed production
Publication Date: 2026.01.20 MONSANTO TECHNOLOGY LLC
  • US12527250B2 patent drawing
  • US12527250B2 patent drawing
  • US12527250B2 patent drawing

AI summary

Methods for improving the efficiency and productivity of hybrid corn seed production are provided herein. Various methods to improve the transfer of pollen from male corn plants to female corn plants, and thus increase yield, are provided herein. Without being limiting, these methods include varying the height of male and female corn plants in a field, as well as varying the number, arrangement, and ratio of male-to-female rows in a field.