Hybrid Corn Variety CH010431 for Marker-Guided Trait Selection

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Solution Overview

Problem

Existing corn breeding techniques struggle to combine desirable traits such as yield, disease resistance, and uniformity in a single hybrid variety, often requiring extensive selection and cross-pollination methods that are inefficient and time-consuming.

Innovation Solution

Development of the hybrid corn variety CH010431, which incorporates genetic modifications and cytoplasmic traits like male sterility, herbicide resistance, and disease resistance through methods like backcrossing and genome editing, ensuring uniformity and desirable characteristics.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Productivity

If traditional self-pollination and phenotypic selection methods are used for corn breeding, then breeders can select for desirable traits, but the process becomes extremely time-consuming and inefficient

Engineering Contradiction:
Improvebreeding efficiencyVSAvoidtime required for selection and crossing
Core Design Contradiction:
ProductivityVSLoss of time

Solution Approach 1:

The patent replaces traditional mechanical phenotypic selection with molecular marker-assisted selection. Breeders use DNA markers to identify and select plants with desired genetic traits at the molecular level, eliminating the need for time-consuming phenotypic observation and manual selection processes across multiple generations.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The patent introduces molecular markers as intermediaries between the genotype and phenotype. These markers serve as detectable indicators that allow breeders to indirectly select for desirable traits without waiting for phenotypic expression, significantly accelerating the breeding process.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Adaptability or versatility

If extensive cross-pollination and evaluation of multiple inbred plants are performed to develop hybrid varieties, then desirable traits can be combined, but the device complexity and breeding program complexity increase

Engineering Contradiction:
Improveability to combine desirable traitsVSAvoidbreeding program complexity
Core Design Contradiction:
Adaptability or versatilityVSDevice complexity

Solution Approach 1:

The patent implements feedback mechanisms through molecular marker analysis at various stages of the breeding process. By continuously monitoring the genetic composition of breeding populations and individual plants, breeders can make informed decisions about which plants to advance, cross, or discard, streamlining the complex process of combining multiple desirable traits.

Inventive Principle:
Principle #23Feedback

Solution Approach 2:

The patent segments the complex breeding program into distinct molecular marker-guided selection steps. Instead of managing complexity through extensive phenotypic evaluation, the breeding process is divided into manageable stages where specific marker sets are used to select for specific traits, making the overall program more controllable and efficient.

Inventive Principle:
Principle #1Segmentation

3Manufacturing precision

If traditional breeding methods are used to achieve uniformity in germination, stand establishment, and growth, then phenotypic uniformity can be selected, but the manufacturing precision and consistency of traits are insufficient

Engineering Contradiction:
Improveuniformity of germination and growth traitsVSAvoidease of selecting uniform traits
Core Design Contradiction:
Manufacturing precisionVSEase of manufacture

Solution Approach 1:

The patent replaces phenotypic selection for uniformity with molecular marker-based genotypic selection. By selecting plants with identical or highly similar genetic profiles at the marker level, breeders achieve precise uniformity in germination, stand establishment, and growth traits without relying on imprecise phenotypic observations.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Data Source

PatentUS12364237B2Plants and seeds of hybrid corn variety CH010431
Publication Date: 2025.07.22 MONSANTO TECHNOLOGY LLC

AI summary

According to the invention, there is provided seed and plants of the hybrid corn variety designated CH010431. The invention thus relates to the plants, seeds and tissue cultures of the variety CH010431, and to methods for producing a corn plant produced by crossing a corn plant of variety CH010431 with itself or with another corn plant, such as a plant of another variety. The invention further relates to genetic complements of plants of variety CH010431.