Hybrid Corn Variety Breeding for Stable Traits and Hybrid Vigor

Resolve Bottlenecks,
Find Innovative Solutions
Generate Solutions

Solution Overview

Problem

Existing corn breeding techniques struggle to develop hybrids with uniformity and stability, incorporating desirable traits such as yield, disease resistance, and drought tolerance, while maintaining genetic diversity and avoiding self-pollination.

Innovation Solution

The development of the hybrid corn variety CH010565, which includes genetic modifications for traits like male sterility, herbicide resistance, and disease resistance, achieved through backcrossing and genetic transformation techniques, ensuring uniformity and stability.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If conventional breeding techniques are used to develop corn hybrids, then genetic diversity is maintained, but uniformity and stability of desirable traits are difficult to achieve

Engineering Contradiction:
Improveuniformity and stability of desirable traitsVSAvoidbreeding process complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The patent extracts and isolates specific desirable traits (such as disease resistance, yield components, stress tolerance) into distinct inbred lines through repeated self-pollination and selection. This allows each trait to be developed and stabilized independently before being combined in hybrid crosses, resolving the contradiction between maintaining genetic diversity and achieving uniformity of specific traits.

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The breeding program segments the corn genome into distinct inbred parental lines, each carrying specific desirable alleles. By dividing the complex breeding process into separate stages (developing inbred A, developing inbred B, then crossing them), the patent achieves both trait uniformity in the hybrid and management of breeding complexity through modular development.

Inventive Principle:
Principle #1Segmentation

2Ease of manufacture

If self-pollination is allowed in corn breeding, then breeding process is simplified, but genetic uniformity increases which reduces hybrid vigor

Engineering Contradiction:
Improvebreeding process simplicityVSAvoidhybrid vigor and yield
Core Design Contradiction:
Ease of manufactureVSProductivity

Solution Approach 1:

The patent applies preliminary self-pollination and selection to develop highly homozygous inbred lines before the crossing stage. This preliminary action creates genetically uniform parents with stable, predictable trait expression, which then produce vigorous hybrids when crossed. The self-pollination is used strategically only in the preliminary stages, not in the final hybrid production.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

Instead of allowing continuous self-pollination to maintain simplicity, the patent inverts the approach by using self-pollination to create uniform parents, then switching to cross-pollination to generate hybrid vigor. The breeding process alternates between selfing (for uniformity) and crossing (for vigor) depending on the stage, resolving the contradiction between simplicity and productivity.

Inventive Principle:
Principle #13The other way round (Inversion)

3Productivity

If multiple desirable traits are combined in a single hybrid, then overall performance improves, but breeding time and complexity increase

Engineering Contradiction:
Improveoverall hybrid performanceVSAvoidbreeding program duration
Core Design Contradiction:
ProductivityVSLoss of time

Solution Approach 1:

The patent merges multiple desirable traits from different inbred parental lines into a single hybrid offspring. By accumulating desirable alleles from both parents (e.g., disease resistance from one parent, yield traits from the other), the hybrid achieves superior overall performance combining multiple traits that neither parent possessed alone.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The patent performs preliminary selection and development of parental lines that already possess specific desirable traits before the crossing stage. This preliminary action ensures that when the cross is made, the hybrid inherits multiple pre-selected traits simultaneously, reducing the time needed to develop each trait separately in the hybrid generation.

Inventive Principle:
Principle #10Preliminary action

4Reliability

If inbred lines are developed through repeated selfing, then genetic uniformity increases, but inbreeding depression reduces plant vigor

Engineering Contradiction:
Improvegenetic uniformity of parental linesVSAvoidplant vigor during inbreeding
Core Design Contradiction:
ReliabilityVSStrength

Solution Approach 1:

The patent applies preliminary selection pressure during the inbreeding process to maintain vigor. By selecting the most vigorous individuals for continued selfing at each generation, the program maintains plant strength despite repeated self-pollination. This preliminary selection during inbreeding prevents severe inbreeding depression while achieving the necessary genetic uniformity.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The patent converts the potential harm of inbreeding depression into a benefit by using the uniformity achieved through selfing to create highly predictable parental lines. The slight reduction in vigor during inbreeding is acceptable because it creates genetically stable parents that will produce vigorous hybrids when crossed. The harm of reduced parental vigor is disguised by the benefit of hybrid vigor in the final product.

Inventive Principle:
Principle #22Blessing in disguise (Convert harm into benefit)

Data Source

PatentUS12568900B2Plants and seeds of hybrid corn variety CH010565
Publication Date: 2026.03.10 MONSANTO TECHNOLOGY LLC

AI summary

According to the disclosure, there is provided seed and plants of the hybrid corn variety designated CH010565. The disclosure thus relates to the plants, seeds, and tissue cultures of the variety CH010565, and to methods for producing a corn plant produced by crossing a corn plant of variety CH010565 with itself or with another corn plant, such as a plant of another variety. The disclosure further relates to genetic complements of plants of variety CH010565.