Hybrid Corn Variety Breeding for Uniform Traits and Hybrid Vigor

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Solution Overview

Problem

Existing corn breeding methods struggle to develop hybrids with stable, uniform, and desirable traits such as increased yield, disease resistance, and drought tolerance while maintaining genetic diversity and uniformity.

Innovation Solution

The development of the hybrid corn variety CH010536, which incorporates cytoplasmic and nuclear factors for male sterility, genetic modifications for traits like herbicide resistance and disease resistance, and a method of controlled cross-pollination to ensure uniformity and stability, along with tissue culture for regenerable cells to maintain desired characteristics.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Stability of the object's composition

If traditional breeding methods are used to develop corn hybrids, then genetic diversity can be maintained, but achieving uniformity and stability of desirable traits across generations becomes difficult

Engineering Contradiction:
Improveuniformity of desirable traitsVSAvoidbreeding process complexity
Core Design Contradiction:
Stability of the object's compositionVSDevice complexity

Solution Approach 1:

The patent applies preliminary action by pre-establishing homozygous inbred parental lines with stable, uniform genetics before crossing. This ensures that the F1 hybrid generation will exhibit consistent and stable desirable traits across all plants, resolving the contradiction between trait uniformity and breeding complexity.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The patent changes the genetic parameter state by creating completely homozygous inbred lines (100% homozygosity) as parents, which then produce F1 hybrids with uniform heterozygosity. This parameter change ensures stable expression of desirable traits while maintaining a manageable breeding process.

Inventive Principle:
Principle #35Parameter changes

2Stability of the object's composition

If self-pollination is used to create homozygous lines, then genetic uniformity is achieved, but the ability to produce hybrid vigor and combine desirable traits from different lines is reduced

Engineering Contradiction:
Improvegenetic uniformityVSAvoidhybrid vigor
Core Design Contradiction:
Stability of the object's compositionVSAdaptability or versatility

Solution Approach 1:

The patent segments the breeding process into distinct phases: first creating homozygous inbred lines through self-pollination to achieve genetic uniformity, then crossing these standardized lines to generate F1 hybrids that exhibit hybrid vigor. This segmentation allows both genetic uniformity and hybrid vigor to be achieved at different stages.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The patent performs preliminary self-pollination to create genetically uniform homozygous parental lines before conducting the cross. This preliminary action ensures that when hybrids are produced, they combine desirable traits from both parents while maintaining uniformity and stability across the population.

Inventive Principle:
Principle #10Preliminary action

3Reliability

If multiple breeding generations are advanced to combine traits, then desirable characteristics can be accumulated, but the time required to develop new hybrids increases

Engineering Contradiction:
Improvetrait combination stabilityVSAvoidbreeding cycle duration
Core Design Contradiction:
ReliabilityVSLoss of time

Solution Approach 1:

The patent performs preliminary trait combination and stabilization work in the parental inbred line development stage. By the time F1 hybrid production begins, all desirable traits are already fixed and stabilized in the homozygous parents, eliminating the need for additional generation advancement and significantly reducing breeding cycle time.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The patent changes the breeding approach by using completely homozygous inbred lines (100% homozygosity) as parents, which allows single-generation F1 hybrid production with stable, predictable trait expression. This parameter change eliminates the need for multiple advancement generations while maintaining reliable trait combination.

Inventive Principle:
Principle #35Parameter changes

4Adaptability or versatility

If cross-pollination is used to produce hybrids, then genetic diversity and hybrid vigor are enhanced, but maintaining uniformity and preventing unwanted genetic variation becomes more difficult

Engineering Contradiction:
Improvehybrid vigorVSAvoidgenetic uniformity
Core Design Contradiction:
Adaptability or versatilityVSStability of the object's composition

Solution Approach 1:

The patent changes the genetic parameter state by using completely homozygous inbred lines (100% homozygosity) as parental material. When these standardized lines are crossed, the F1 hybrids exhibit uniform heterozygosity, ensuring both hybrid vigor and genetic uniformity across the entire population.

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent implements feedback through rigorous selection and validation of parental inbred lines to ensure complete homozygosity and desired trait expression before crossing. This feedback mechanism ensures that only genetically uniform parents are used, which guarantees uniform F1 hybrid production while maintaining hybrid vigor.

Inventive Principle:
Principle #23Feedback

Data Source

PatentUS12604828B2Plants and seeds of hybrid corn variety CH010536
Publication Date: 2026.04.21 MONSANTO TECHNOLOGY LLC

AI summary

According to the disclosure, there is provided seed and plants of the hybrid corn variety designated CH010536. The disclosure thus relates to the plants, seeds, and tissue cultures of the variety CH010536, and to methods for producing a corn plant produced by crossing a corn plant of variety CH010536 with itself or with another corn plant, such as a plant of another variety. The disclosure further relates to genetic complements of plants of variety CH010536.