Hybrid Corn Breeding With Controlled Pollination for Uniform Yield

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Solution Overview

Problem

Existing corn breeding techniques struggle to develop hybrids with uniformity and desirable traits such as increased yield, resistance to pests and diseases, and improved agronomic qualities, while maintaining genetic stability and commercial viability.

Innovation Solution

The development of the hybrid corn variety CH010527, which incorporates cytoplasmic or nuclear factors for male sterility, genetic modifications for traits like herbicide resistance and disease resistance, and a method of controlled cross-pollination to ensure uniformity and desirable characteristics, along with the use of genome editing techniques for precise genetic locus modifications.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If conventional corn breeding techniques are used, then hybrid production can be maintained, but uniformity and desired traits such as increased yield and disease resistance are difficult to achieve

Engineering Contradiction:
ImproveuniformityVSAvoidyield
Core Design Contradiction:
ReliabilityVSProductivity

Solution Approach 1:

The patent applies parameter changes by introducing specific genetic modifications (transgenes) and cytoplasmic traits (male sterility) into the corn genome to alter biological parameters. This enables precise control over traits like yield, disease resistance, and uniformity, transforming conventional breeding from qualitative selection to quantitative genetic engineering.

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent uses tissue culture techniques as an intermediary method to propagate hybrid corn plants with uniform genetic characteristics. Tissue culture acts as a mediator between genetic engineering and field production, ensuring consistent trait expression and uniformity across all plants while maintaining the desired agricultural productivity.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Object-affected harmful factors

If genetic modifications and cytoplasmic traits are introduced, then resistance to pests and diseases is improved, but genetic stability and production efficiency may be compromised

Engineering Contradiction:
Improvedisease resistanceVSAvoidgenetic stability
Core Design Contradiction:
Object-affected harmful factorsVSStability of the object's composition

Solution Approach 1:

The patent extracts and isolates specific beneficial traits (disease resistance genes, male sterility cytoplasm) from complex genetic backgrounds and introduces them as discrete, stable elements. By separating these traits from unnecessary genetic variation, the patent maintains genetic stability while achieving targeted disease resistance and pest protection.

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The patent employs male sterility cytoplasm as a temporary, non-heritable factor that ensures cross-pollination efficiency in the F1 generation. This cytoplasmic trait is discarded in subsequent generations, allowing the focus to remain on stable nuclear genes for disease resistance, thus maintaining long-term genetic stability while achieving short-term breeding efficiency.

Inventive Principle:
Principle #27Cheap short-living objects (Disposable)

3Manufacturing precision

If controlled cross-pollination and tissue culture techniques are used, then uniformity in hybrid production is ensured, but production efficiency and time to maturity may be reduced

Engineering Contradiction:
Improveuniformity in hybrid productionVSAvoidtime to crop maturity
Core Design Contradiction:
Manufacturing precisionVSLoss of time

Solution Approach 1:

The patent applies preliminary action by using tissue culture to produce uniform hybrid plants before field planting. This pre-propagation step ensures genetic uniformity and trait consistency is established early, eliminating the need for extensive field selection and reducing the time required for uniform stand establishment, thereby accelerating the overall time to crop maturity.

Inventive Principle:
Principle #10Preliminary action

Data Source

PatentUS12622380B2Plants and seeds of hybrid corn variety CH010527
Publication Date: 2026.05.12 MONSANTO TECHNOLOGY LLC

AI summary

According to the disclosure, there is provided seed and plants of the hybrid corn variety designated CH010527. The disclosure thus relates to the plants, seeds, and tissue cultures of the variety CH010527, and to methods for producing a corn plant produced by crossing a corn plant of variety CH010527 with itself or with another corn plant, such as a plant of another variety. The disclosure further relates to genetic complements of plants of variety CH010527.