Hybrid Machine Learning Model for Medication Efficacy Prediction

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Solution Overview

Problem

Conventional healthcare systems face challenges in accurately selecting optimal medications due to the vast amount of data and complexity, leading to subjective and inefficient decision-making processes.

Innovation Solution

A hybrid machine learning model comprising static and dynamic portions is used to process patient data, generating an efficacy score for medication predictions, which helps in identifying the most effective treatment options and reducing adverse events.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Adaptability or versatility

If conventional healthcare providers manually review patient data to make treatment decisions, then they can apply personal experience and judgment, but the process becomes subjective, time-consuming, and unable to evaluate all relevant data and alternatives

Engineering Contradiction:
Improveability to evaluate all relevant data and alternativesVSAvoidtime required for manual review
Core Design Contradiction:
Adaptability or versatilityVSLoss of time

Solution Approach 1:

The patent replaces the mechanical system of manual human review with an automated machine learning system that processes patient data, medication information, and clinical guidelines to generate efficacy scores and treatment recommendations, eliminating the time-consuming manual evaluation while maintaining or improving decision quality

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The system enables self-service by automatically generating treatment recommendations without requiring extensive human intervention, allowing the computational system to independently evaluate all relevant data, alternatives, and interactions while providing actionable insights to healthcare providers

Inventive Principle:
Principle #25Self-service

2Reliability

If healthcare providers review vast amounts of patient data including contraindications, side effects, and medication interactions, then comprehensive evaluation is possible, but effective or accurate selections become difficult and uncertainty increases

Engineering Contradiction:
Improveaccuracy of medication selectionVSAvoidcomplexity of data evaluation
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The patent segments the complex evaluation process into distinct computational components: the machine learning model evaluates patient data, contraindications, side effects, and medication interactions separately and integrates them into a unified efficacy score, making the complex evaluation manageable and accurate

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The system introduces an intermediary computational layer that processes and synthesizes vast amounts of complex data including contraindications, side effects, and interactions, translating this complexity into simplified, actionable efficacy scores that reduce uncertainty in medication selection

Inventive Principle:
Principle #24Intermediary (Mediator)

3Productivity

If conventional approaches rely on extensive personal experience for adequate results, then subjective judgment is applied, but the process fails to identify the most optimal options and requires extensive time

Engineering Contradiction:
Improveefficiency of treatment decision-makingVSAvoidaccuracy of identifying optimal options
Core Design Contradiction:
ProductivityVSMeasurement precision

Solution Approach 1:

The patent replaces subjective human judgment with an objective machine learning system that consistently evaluates all treatment options based on patient data and clinical evidence, improving both the efficiency and precision of identifying optimal treatment choices without relying on individual provider experience

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The system changes the parameters of decision-making from subjective human factors to objective computational metrics, using efficacy scores derived from patient-specific data to precisely identify optimal treatment options while dramatically improving productivity

Inventive Principle:
Principle #35Parameter changes

Data Source

PatentUS20230298722A1Models to predict medication effectiveness
Publication Date: 2023.09.21 MATRIXCARE INC
  • US20230298722A1 patent drawing
  • US20230298722A1 patent drawing
  • US20230298722A1 patent drawing

AI summary

Techniques for improved machine learning are provided. Patient data describing a patient is received, and a medication to be evaluated with respect to the patient is identified. An efficacy score is generated by processing at least a subset of the patient data using a hybrid machine learning model comprising a static portion and a dynamic portion, where the efficacy score indicates predicted efficacy of the medication for the patient. The medication is provided for the patient based at least in part on the efficacy score.