Hydraulically controlled cryopreservation device

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Solution Overview

Problem

Current cryogenic preservation systems using compressed air to drive a piston lack control over displacement speed and cryogenic preservation conditions, leading to inefficient and uncontrolled rapid freezing processes.

Innovation Solution

A cryogenic preservation device utilizing a hydraulic circuit with a pressurized hydraulic oil accumulator, control system, and piston configuration to control the speed and pressure of hydraulic oil displacement, allowing precise control over cryogenic fluid delivery and preservation conditions.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Speed

If compressed air expansion is used to drive the piston, then high displacement velocities of liquid nitrogen can be achieved, but the temperature and pressure conditions cannot be controlled and the piston speed cannot be controlled

Engineering Contradiction:
Improvepiston displacement speedVSAvoidcontrol over cryogenic preservation conditions
Core Design Contradiction:
SpeedVSReliability

Solution Approach 1:

The patent replaces the compressed air expansion system with a hydraulic system using incompressible fluid. The hydraulic cylinder receives pressurized hydraulic fluid through a controllable valve, enabling both high-speed piston displacement and precise control of temperature and pressure conditions during cryogenic preservation

Inventive Principle:
Principle #29Pneumatics and hydraulics

2Reliability

If hydraulic systems are used to drive the piston rapidly, then controlled displacement speed can be achieved, but the viscosity of hydraulic oils prevents rapid displacement

Engineering Contradiction:
Improvecontrol over displacement speedVSAvoidpiston displacement speed
Core Design Contradiction:
ReliabilityVSSpeed

Solution Approach 1:

The patent changes the physical parameters of the hydraulic system by using a low-viscosity hydraulic fluid and significantly increasing the system pressure (using pressurized hydraulic fluid storage at high pressure). This allows the hydraulic fluid to flow rapidly despite its viscosity, enabling both speed and control requirements to be met simultaneously

Inventive Principle:
Principle #35Parameter changes

3Speed

If gas expansion with more energy is used, then higher displacement speeds can be achieved, but the control and regulation devices become more complex

Engineering Contradiction:
Improvepiston displacement speedVSAvoidcontrol and regulation devices
Core Design Contradiction:
SpeedVSDevice complexity

Solution Approach 1:

The patent adopts a hydraulic system with pressurized fluid storage instead of high-energy gas expansion. The pre-pressurized hydraulic fluid in the storage device provides the necessary energy for rapid piston displacement without requiring complex control and regulation devices, as the hydraulic system inherently provides better controllability

Inventive Principle:
Principle #29Pneumatics and hydraulics

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Enables rapid and controlled cryogenic preservation with precise control over temperature and pressure conditions, reducing preservation times and ensuring efficient cryogenic fluid delivery, thereby improving the cryogenic preservation process.

Implementation Method 1

a cylinder including a piston configured to be driven by the second volume of hydraulic oil and to drive a first volume of cryogenic fluid

Methodology Applied
Scientific EffectHydraulic pressure transmission: Hydraulic Press

Implementation Method 2

the accumulator includes a chamber, the volume whereof is deformable and wherein a volume of compressible gas produces a predefined pressure to which the first volume of hydraulic oil of the accumulator is subjected

Methodology Applied
Scientific EffectGas compression: Compression

Implementation Method 3

the geometrical configuration of the piston ensures a pressure ratio between the inlet thereof and the outlet thereof that is greater than or equal to 6

Methodology Applied
Scientific EffectPressure ratio transformation: Hydraulic Press

Data Source

PatentUS11650007B2Hydraulically controlled cryopreservation device
Publication Date: 2023.05.16 CRYOCAPCELL
  • US11650007B2 patent drawing
  • US11650007B2 patent drawing

AI summary

This cryogenic preservation or vitrification device (1) comprises:an accumulator (2) including a first volume of pressurised hydraulic oil;a control system controlling a valve (20) capable of releasing a second volume of hydraulic oil from the accumulator toward a cylinder (55) by means of a pipe (4);a cylinder (55) including a piston (6) configured to be driven by the second volume of hydraulic oil and to displace a first volume of cryogenic fluid to a cryogenic vessel (7) intended to receive a sample (8) to be cryogenically preserved.