Hydrocyanation Catalyst Stabilization via Water Control

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Solution Overview

Problem

The hydrocyanation of 3-pentenenitrile to produce adiponitrile faces challenges with catalyst deactivation and inefficient use of phosphorus-containing ligands due to degradation products accumulating in recycle loops, leading to reduced catalytic activity.

Innovation Solution

A process involving a hydrocyanation reaction zone with controlled water concentration between 100 ppm to 300 ppm, using a catalyst complex of nickel and a bidentate phosphorus-containing ligand, along with a Lewis acid promoter, to maintain catalyst activity and suppress degradation, allowing for efficient recycling and reuse of the catalyst.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Productivity

If the catalyst complex is recycled through extraction and reuse, then productivity is improved, but the phosphorus-containing ligand degrades and catalytic activity decreases

Engineering Contradiction:
Improvecatalyst reuse efficiencyVSAvoidcatalyst activity stability
Core Design Contradiction:
ProductivityVSReliability

Solution Approach 1:

The patent changes the physical-chemical parameters of the extraction system by introducing a basic extraction solvent (containing amines or amides) to alter the chemical environment during catalyst recovery. This parameter change prevents ligand degradation while maintaining extraction efficiency, allowing the catalyst to be reused with retained activity

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The basic extraction solvent acts as an intermediary substance that protects the phosphorus-containing ligand from degradation during the extraction process. The base neutralizes acidic degradation products and prevents catalyst deactivation, enabling successful catalyst recycling without direct contact between the ligand and degrading conditions

Inventive Principle:
Principle #24Intermediary (Mediator)

2Ease of operation

If conventional extraction solvents are used to recover catalyst, then ease of operation is improved, but catalyst deactivation increases due to ligand hydrolysis and disproportionation

Engineering Contradiction:
Improvecatalyst recovery simplicityVSAvoidcatalyst complex stability
Core Design Contradiction:
Ease of operationVSReliability

Solution Approach 1:

The patent modifies the chemical parameter of the extraction solvent from neutral/conventional to basic (pH-adjusted), which fundamentally changes the extraction environment. This parameter change suppresses hydrolysis and disproportionation reactions of the phosphorus ligand while maintaining the simplicity of the extraction operation

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent converts the potentially harmful effect of water (which causes hydrolysis) into a benefit by using a basic environment that neutralizes acidic degradation products. The water present in the system, which would normally degrade the ligand, is instead converted into a benign component by the basic extraction solvent that prevents degradation

Inventive Principle:
Principle #22Blessing in disguise (Convert harm into benefit)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This process effectively stabilizes the catalyst complex, maintaining high catalytic activity through successive recycle cycles, reducing deactivation to less than 5% and improving the overall efficiency of adiponitrile production by inhibiting degradation and hydrolysis of the bidentate phosphorus ligand.

Implementation Method 1

The hydrocyanation of 3-pentenenitrile to produce adiponitrile faces challenges with catalyst deactivation and inefficient use of phosphorus-containing ligands

Methodology Applied
Scientific EffectCatalysis: Catalysis

Implementation Method 2

controlling the amount of water in the catalyst complex recharged to the reaction zone so that the concentration of water in the reaction zone is 100 to 300 ppm to decrease the total percentage deactivation percentages established

Methodology Applied
Scientific EffectHydrolysis suppression: Hydrolysis

Data Source

PatentEP2763960B1Process for making nitriles
Publication Date: 2017.03.01 INVISTA TECHNOLOGIES SARL(CH)
  • EP2763960B1 patent drawingFigure 1
  • EP2763960B1 patent drawingFigure 2~3
  • EP2763960B1 patent drawingFigure 4~5

AI summary

The present invention relates to a process for hydrocyanating 3-pentene¬ nitrile. The process can include feeding 3-pentenenitrile and HCN to a hydrocyanation reaction zone that includes a Lewis acid promoter, nickel, and a phosphorus-containing ligand. In various embodiments, the process can also include controlling water concentration within the hydrocyanation reaction zone sufficient to maintain a high activity of the ligand catalyst complex while recycling at least a portion of the ligand catalyst complex.