Biocompatible Sensor Device with Hydrogel Capacitance

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Solution Overview

Problem

Conventional analytical biosensors face limitations such as signal drift, dependence on degradative reference electrodes, and bulky wireless formats, making them unsuitable for long-term, continuous monitoring of complex aqueous environments and requiring the development of versatile, flexible, and biocompatible sensor architectures with properties like stretchability and diverse analytical sensing capabilities.

Innovation Solution

The development of a sensor device with a hydrogel interlayer and planar metallic structures that respond to environmental stimuli by modifying capacitance and generating electrical signals, allowing for passive, wireless, and biocompatible monitoring without integrated batteries or microelectronics, enabling long-term stability and diverse analytical sensing.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If conventional analytical biosensors are used, then sensing capability is achieved, but signal drift and long-term stability are compromised

Engineering Contradiction:
Improvelong-term stabilityVSAvoidsignal drift
Core Design Contradiction:
ReliabilityVSMeasurement precision

Solution Approach 1:

The patent replaces conventional electrochemical sensing mechanisms with a capacitive sensing mechanism using a hydrogel dielectric layer. The hydrogel's capacitance changes in response to environmental stimuli (pH, temperature, ionic strength) without requiring degradative reference electrodes, thereby eliminating signal drift while maintaining long-term stability for continuous monitoring applications.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The patent utilizes changes in the hydrogel's physical and chemical parameters (swelling, shrinking, phase transitions) in response to environmental stimuli to modulate capacitance. This allows the sensor to detect pH, temperature, and ionic strength changes through measurable capacitance variations, providing stable long-term sensing without signal drift.

Inventive Principle:
Principle #35Parameter changes

2Ease of operation

If conventional wireless sensor formats are used, then wireless monitoring is achieved, but device size becomes bulky

Engineering Contradiction:
Improvewireless functionVSAvoiddevice size
Core Design Contradiction:
Ease of operationVSVolume of moving object

Solution Approach 1:

The patent employs thin-film planar metallic structures separated by a thin hydrogel dielectric layer, creating a compact capacitive sensor that can be fabricated on flexible substrates. This thin-film architecture enables wireless sensing functionality while maintaining a minimal device footprint suitable for conformal and implantable applications.

Inventive Principle:
Principle #30Flexible shells and thin films

Solution Approach 2:

The patent transitions from bulky three-dimensional wireless sensor housings to planar two-dimensional capacitive structures. By utilizing planar metallic electrodes and thin hydrogel layers, the sensor achieves wireless monitoring capability with dramatically reduced volume, enabling integration into flexible and conformal device formats.

Inventive Principle:
Principle #17Another dimension (Dimensionality change)

3Adaptability or versatility

If conventional medical devices are used, then monitoring capability is achieved, but flexibility and conformal interface are compromised

Engineering Contradiction:
Improvemonitoring capabilityVSAvoidflexibility
Core Design Contradiction:
Adaptability or versatilityVSShape

Solution Approach 1:

The patent utilizes flexible substrate materials and thin-film fabrication techniques to create sensor devices that can conform to complex biological surfaces and tissues. The flexible architecture maintains full monitoring capability while enabling conformal interfaces for enhanced patient comfort and continuous physiological parameter tracking.

Inventive Principle:
Principle #30Flexible shells and thin films

Solution Approach 2:

The patent designs a universal sensor platform with planar metallic structures and hydrogel dielectric that can detect multiple environmental stimuli (pH, temperature, ionic strength) through capacitance changes. This multi-functional design provides versatile monitoring capability across different physiological parameters while maintaining flexibility and conformal interface properties.

Inventive Principle:
Principle #6Universality (Multi-functionality)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The sensor device achieves long-term, biocompatible, and versatile monitoring of environmental stimuli, providing continuous and flexible data collection in complex environments with enhanced stability and reduced signal drift, suitable for healthcare applications.

Implementation Method 1

modifying a capacitance of a hydrogel in response to the received environmental stimulus

Methodology Applied
Scientific EffectCapacitance: Capacitance

Implementation Method 2

The inner hydrogel layer may undergo swelling or shrinking in response to the environmental stimulus, which may enable detection of the environmental stimulus

Methodology Applied
Scientific EffectHydrogel swelling/shrinking: Hydrogel

Implementation Method 3

modifying the capacitance of the hydrogel by modifying a resonant frequency of the hydrogel

Methodology Applied
Scientific EffectResonant frequency: Resonance

Data Source

PatentUS20220255356A1Biocompatible sensor device and method for detecting environmental stimuli therewith
Publication Date: 2022.08.11 RGT UNIV OF CALIFORNIA
  • US20220255356A1 patent drawing
  • US20220255356A1 patent drawing
  • US20220255356A1 patent drawing

AI summary

A sensor device includes an inner hydrogel layer, a first planar metallic structure adjacent to a first surface of the inner hydrogel layer, and a second planar metallic structure adjacent to a second surface of the inner hydrogel layer opposite to the first surface. A sensor device further includes an encasing layer at least partially enclosing at least one of the inner hydrogel layer, the first planar metallic structure, and the second planar metallic structure. A method for use of the sensor device includes receiving at least one environmental stimulus, modifying a capacitance of a hydrogel in response to the received environmental stimulus, and generating an electrical stimulus response based on the modified capacitance. The method further includes modifying the capacitance of the hydrogel by modifying a resonant frequency of the hydrogel.