Hydrogel Penis Patch With Zoned Drug Delivery for Premature Ejaculation
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Solution Overview
Problem
Existing treatments for premature ejaculation, such as oral medications, topical treatments, and surgical interventions, often come with side effects, are not universally suitable, and herbal therapies lack robust evidence, while conventional patches do not conform to the penis's complex curvature, leading to discomfort and uneven drug distribution.
Innovation Solution
A disposable hydrogel patch with a 3D ergonomic design and dual drug zones that conform to the penile coronal sulcus, delivering natural and synthetic ingredients to target the dorsal nerve and promote vasodilation, using a hydrogel coating for controlled release and comfort.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Manufacturing precision
If conventional patches are used for PE treatment, then drug delivery is achieved, but the patch does not conform to the penis's complex curvature leading to discomfort and uneven drug distribution
Solution Approach 1:
The patch incorporates a 3D ergonomic design with curved surfaces that match the natural contours of the penile coronal sulcus. The patch includes protruding structures (hemispherical, semi-cylindrical, or semi-vertebral) that embed into the coronal sulcus recess, creating a conformal fit that ensures uniform drug distribution across the target area while maximizing comfort during wear.
2Duration of action of moving object
If topical anesthetic treatments are used to delay ejaculation, then ejaculation time is prolonged, but side effects include erectile dysfunction, reduced sexual sensitivity, and allergic reactions
Solution Approach 1:
The patch employs differentiated drug delivery with distinct drug mixtures in different zones: the central zone contains first drug mixture (anesthetics like lidocaine or benzocaine) for ejaculation control, while side zones contain second drug mixture (vasodilators like sildenafil or tadalafil) for erection support. This spatial differentiation allows targeted treatment of specific penile regions, providing ejaculation latency prolongation while minimizing systemic absorption and associated side effects through localized action.
3Duration of action of moving object
If oral medications are used for PE treatment, then ejaculation is delayed, but side effects include nausea, dizziness, xerostomia, and decreased libido
Solution Approach 1:
The patch serves as a local intermediary delivery system that places medication directly onto the penile surface, bypassing first-pass metabolism and systemic circulation. This localized delivery mechanism through the hydrogel matrix reduces systemic absorption of active ingredients, thereby minimizing systemic side effects such as nausea, dizziness, and decreased libido while maintaining effective local concentrations for ejaculation control.
4Duration of action of moving object
If surgical interventions are used to delay ejaculation, then penile sensitivity is reduced, but the procedure is invasive and irreversible with risks of paralysis and erectile dysfunction
Solution Approach 1:
The patch is designed as a disposable, non-invasive alternative to permanent surgical interventions. The patch can be applied and removed without surgical incisions, avoiding permanent tissue damage, nerve injury, or erectile dysfunction. The temporary nature of the patch allows for reversible treatment, eliminating the need for irreversible surgical modification while achieving similar ejaculation control effects through localized drug delivery.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
Effectively delays ejaculation, prolongs erection time, minimizes discomfort, and enhances sexual pleasure by precisely targeting the dorsal nerve and improving blood circulation without systemic absorption or side effects.
Implementation Method 1
The hydrogel coating covers the drug-loaded strip, controlling the sustained release of drug components, achieving stable and smooth release
Implementation Method 2
Hydrogels are three-dimensional networks of hydrophilic polymers that can absorb and retain large amounts of water
Data Source
AI summary
This invention presents a disposable male hydrogel patch designed to delay ejaculation and prolong erection time while minimizing the impact on sexual pleasure. The patch features an ergonomically designed backing with specific curvatures, a drug-loaded strip divided into central and side zones, and an optional hydrogel coating for sustained drug release. The central zone contains a drug mixture that inhibits the dorsal nerve of the penis, while the side zones promote vasodilation related to erection. The backing includes the adjustment hole for adaptive fitting and is made of a multi-layer composite that integrates breathability, waterproofing, moisture absorption, and fixation. The drug-loaded strip incorporates herbal extracts and synthetic compounds to target the nervous system, vascular system, and endocrine system. Discrete protruding arrays at the coronal sulcus recess enhance drug delivery. This novel, multi-angle approach comprehensively improves sexual function and quality of life, making it a significant innovation in male sexual health.