Optical Hydrogel Refractive Index Modification for Post-Implantation Vision Correction
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Solution Overview
Problem
Existing intraocular lenses (IOLs) cannot be adjusted post-implantation to correct vision errors due to errors in measurement, variable lens positioning, or wound healing, necessitating additional corrective measures like glasses or contact lenses.
Innovation Solution
An optical device comprising an optical hydrogel with select regions irradiated by a laser to modify the refractive index, allowing for adjustment of the lens power post-implantation by increasing the refractive index in specific regions.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Ease of operation
If a fixed power intraocular lens is implanted, then the surgical procedure is simple and quick, but the patient requires additional corrective lenses due to measurement errors or positioning variability
Solution Approach 1:
The patent applies the dynamics principle by transforming a static, fixed-power intraocular lens into a dynamic system where the refractive index can be modified post-implantation. The lens incorporates a refraction modulating composition that allows change in optical properties after surgery, enabling adjustment of vision correction accuracy without requiring surgical revision.
Solution Approach 2:
The patent implements parameter changes by modifying the refractive index of the lens material through light-induced polymerization. The refraction modulating composition undergoes chemical transformation when exposed to light, changing the physical parameter of refractive index to adjust the lens power and correct vision errors that occurred during surgery.
2Adaptability or versatility
If the first polymer matrix is made loose to allow RMC diffusion, then adaptability improves, but manufacturing precision decreases due to component migration
Solution Approach 1:
The patent applies preliminary action by pre-distributing the refraction modulating composition uniformly throughout the lens material during manufacturing. This initial uniform distribution ensures manufacturing precision is maintained, while the loose polymer matrix structure is deliberately designed to allow subsequent diffusion and migration of RMC components during the light-adjustment process, achieving both precision and adaptability.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
Enables precise correction of vision errors and aberrations by modifying the refractive index of the intraocular lens post-implantation, improving patient vision without the need for additional corrective lenses.
Implementation Method 1
The light-adjustable lens is said to comprise (i) a first polymer matrix and (ii) a refraction modulating composition (RMC) that is capable of stimulus-induced polymerization. As stated, when a portion of the described lens is exposed to light of sufficient intensity, the RMC forms a second polymer matrix.
Data Source
AI summary
An optical device comprising an optical hydrogel with select regions that have been irradiated with laser light having a pulse energy from 0.01 nJ to 50 nJ and a wavelength from 600 nm to 900 nm. The irradiated regions are characterized by a positive change in refractive index of from 0.01 to 0.06, and exhibit little or no scattering loss. The optical hydrogel is prepared with a hydrophilic monomer.