Hydrogel Surgical Training Aids for Tissue Property Replication

Resolve Bottlenecks,
Find Innovative Solutions
Generate Solutions

Solution Overview

Problem

Current surgical training methods using synthetic models fail to accurately replicate the mechanical and visco-elastic properties of real tissues, limiting their effectiveness as teaching tools for surgical skills development.

Innovation Solution

Hydrogel-based surgical training devices are developed, which mimic the mechanical properties of real tissues by altering processing and composition parameters, such as thermal cycling and strain application, to create multilayer hydrogels that approximate the feel and behavior of organs like skin and cardiovascular tissues.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If traditional synthetic models (silicone rubber, polyurethane, PVC, foam) are used, then the models are easy to manufacture and cost-effective, but they fail to replicate the mechanical and visco-elastic properties of real tissues

Engineering Contradiction:
Improveaccuracy of mechanical property replicationVSAvoidmanufacturing complexity
Core Design Contradiction:
ReliabilityVSEase of manufacture

Solution Approach 1:

The patent applies parameter changes by adjusting the composition ratios of hydrogel components (polymer concentration, crosslinker amount, water content) and processing parameters (temperature, pH, mixing speed) to achieve specific mechanical properties. By varying these parameters, the hydrogel can be tuned to match the visco-elastic properties of different tissues while maintaining manufacturability through standardized formulation processes.

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent uses composite materials by combining multiple components in the hydrogel formulation, including polymers, crosslinkers, plasticizers, and functional additives. This composite approach allows the material to exhibit both the desired mechanical properties and ease of manufacture, as each component contributes specific characteristics that can be optimized independently.

Inventive Principle:
Principle #40Composite materials

2Reliability

If hydrogels are formulated to accurately replicate tissue mechanical properties, then the training realism is improved, but the formulation and processing become more complex

Engineering Contradiction:
Improverealism of tissue replicationVSAvoidformulation complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The patent applies segmentation by dividing the hydrogel formulation into distinct functional components (base polymer, crosslinker, plasticizer, functional additives) with specific roles. This allows complex tissue properties to be achieved through systematic combination of simpler components, making the formulation process more manageable and less complex while maintaining high realism.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The patent applies local quality by tailoring the hydrogel composition to specific tissue types, creating different formulations for different tissues (e.g., vascular tissue vs. soft tissue). Each formulation is optimized for the specific mechanical properties of its target tissue, achieving high realism without requiring all possible formulations to be equally complex.

Inventive Principle:
Principle #3Local quality

3Manufacturing precision

If multilayer hydrogel structures are created to approximate organ properties, then the training accuracy is improved, but the fabrication process becomes more complex

Engineering Contradiction:
Improveaccuracy of organ property approximationVSAvoidfabrication process complexity
Core Design Contradiction:
Manufacturing precisionVSDevice complexity

Solution Approach 1:

The patent applies segmentation by creating separate hydrogel layers, each formulated to approximate the mechanical properties of specific organ layers or tissue types. This allows complex organ properties to be built up from simpler individual layers, improving manufacturing precision while managing fabrication complexity through modular assembly.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The patent applies dimensionality change by transitioning from single-layer to multilayer structures, adding the dimension of layering to the hydrogel fabrication. This enables approximation of complex organ properties through stacked simplified layers, improving accuracy without requiring each layer to be as complex as the entire organ structure.

Inventive Principle:
Principle #17Another dimension (Dimensionality change)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

These hydrogel-based devices provide a realistic surgical training experience, enhancing the accuracy and practicality of surgical skills training by closely replicating the mechanical properties of real tissues, thus overcoming the limitations of existing synthetic models.

Implementation Method 1

thermally cycling the solution through at least one freeze-thaw cycle to form a polyvinyl alcohol hydrogel layer within the mold

Methodology Applied
Scientific EffectFreeze-thaw cycling: Phase Change

Implementation Method 2

the mechanical and visco-elastic response of real tissues is reproduced with improved accuracy

Methodology Applied
Scientific EffectVisco-elasticity: Viscoelasticity

Data Source

PatentUS8870576B2Surgical training aids and methods of fabrication thereof
Publication Date: 2014.10.28 UNIVERSITY OF WESTERN ONTARIO
  • US8870576B2 patent drawing
  • US8870576B2 patent drawing
  • US8870576B2 patent drawing

AI summary

The present invention provides surgical training aids formed from hydrogels and adapted to exhibit realistic mechanical properties mimicking those of real organs. Surgical training aids are preferably fabricated by subjecting a concentration of polyvinyl alcohol to freeze-thaw cycles in a mold designed to approximate the shape of an organ, and process parameters are selected to tailor the mechanical properties of the formed hydrogel to those of the organ simulated by the surgical aid. The mechanical properties of the hydrogel forming the surgical training aid may be tailored by incorporating bacterial cellulose and by applying strain during hydrogel formation, thereby producing controlled anisotropy.