Oral Hygiene Composition Combining Hydrogen Peroxide and Eugenol
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Solution Overview
Problem
Current oral hygiene products, including toothpastes and mouthwashes, are ineffective in curing and preventing periodontal illnesses and halitosis, despite frequent usage, as they fail to adequately address the anaerobic and aerobic bacteria causing these conditions.
Innovation Solution
A pharmaceutical composition comprising Hydrogen Peroxide, Eugenol, Permonochlorophenol, Camphor, Maltitol, a sweetening agent, coloring matter, and demineralized water, designed as a mouthwash or toothpaste, which effectively targets and eliminates anaerobic bacteria, reduces inflammation, and addresses halitosis through its antimicrobial and antiseptic properties.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Productivity
If conventional oral hygiene products (toothpastes, mouthwashes) are used frequently, then oral hygiene maintenance is improved, but effectiveness in curing and preventing periodontal illnesses and halitosis remains insufficient
Solution Approach 1:
The patent changes the chemical parameters of the oral hygiene composition by incorporating hydrogen peroxide (0.01-0.5%) as an active antimicrobial agent, along with eugenol (0.001-0.5%), permonochlorophenol (0.001-0.5%), and camphor (0.001-0.3%). These specific concentration ranges of active ingredients provide enhanced antimicrobial activity against anaerobic and aerobic bacteria compared to conventional products, thereby improving clinical efficacy in treating periodontal illnesses and halitosis.
Solution Approach 2:
The patent creates a composite pharmaceutical composition combining multiple active ingredients (hydrogen peroxide, eugenol, permonochlorophenol, camphor) with sweetening agents and coloring matters. This composite formulation synergistically enhances the antimicrobial and anti-inflammatory effects, achieving superior clinical results in preventing and treating periodontal diseases and halitosis compared to single-activeingredient products.
2Object-affected harmful factors
If conventional oral hygiene products are used, then daily oral cleaning is maintained, but they fail to adequately address anaerobic and aerobic bacteria causing periodontal conditions
Solution Approach 1:
The patent utilizes hydrogen peroxide (0.01-0.5%) as a strong oxidant that actively destroys anaerobic and aerobic bacteria through oxidation of their cellular components. This oxidative mechanism provides superior antimicrobial effectiveness compared to conventional non-oxidizing agents, directly addressing the harmful bacterial factors in periodontal conditions and halitosis.
Solution Approach 2:
The patent employs eugenol (0.001-0.5%) and permonochlorophenol (0.001-0.5%) as intermediary antimicrobial agents that enhance the overall antimicrobial effectiveness. These substances act as mediators that complement hydrogen peroxide's oxidative action, providing broad-spectrum coverage against both anaerobic and aerobic bacteria, thereby improving reliability in eliminating harmful oral microbiota.
3Reliability
If existing oral hygiene formulations are used, then basic hygiene maintenance is achieved, but gingival inflammation and bacterial plaque formation are not effectively prevented
Solution Approach 1:
The patent converts the potentially harmful effect of hydrogen peroxide oxidation into a beneficial anti-inflammatory action. The oxidative mechanism that could damage tissues is controlled and directed to specifically eliminate bacteria and reduce gingival inflammation. Camphor (0.001-0.3%) further enhances this by providing direct anti-inflammatory effects, transforming the formulation into an effective preventive treatment for gingival conditions.
Solution Approach 2:
The patent optimizes the concentration parameters of active ingredients to achieve effective prevention of gingival inflammation. The specific ranges of hydrogen peroxide (0.01-0.5%), eugenol (0.001-0.5%), permonochlorophenol (0.001-0.5%), and camphor (0.001-0.3%) are calibrated to provide sufficient antimicrobial and anti-inflammatory activity while maintaining safety, thereby reliably preventing gingival inflammation and bacterial plaque formation.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The composition effectively reduces gingival inflammation, prevents bacterial plaque formation, and eliminates halitosis when used three times a day, as clinically tested on 28 patients, demonstrating its efficacy in treating and preventing periodontal issues.
Implementation Method 1
Hydrogen Peroxide, in concentrations of 0.001 to 0.5%, is enough effective to destroy of the anaerobic bacteria
Implementation Method 2
Its action and activation is favored by the Catalasa, a salivary enzyme. With this effervescence, the liberation of oxygen from the Peroxide destroys the strict anaerobic microorganisms
Implementation Method 3
The Permonochlorophenol is an antiseptic and antimicrobial compound of a disinfectant action
Implementation Method 4
The Eugenol, is an essential oil derived from the tent oil in concentration of between 0.01 and 0.05%. It also produces an antiseptic, antibacterial and disinfectant effect
Implementation Method 5
The Camphor, present in concentrations of 0.001 to 0.3% exercises an action ant inflammatory in the oral mucosa, in the periodontal tissues and in gums
Implementation Method 6
Maltitol has been used as a synthetic sweetening entity in this mouthwash, in ranges of 10 to 40%. Maltitol is a polyalcohol that, besides its nature of alcohol, it helps to preserve and to stabilize the activity of the Peroxide
Data Source
AI summary
The invention is a pharmaceutical composition for the oral hygiene for the treatment of the periodontal illnesses and the Halitosis. It consists of a mixture 0.01 to 5 g of Hydrogen Peroxide; 0.001 to 0.5 g of Eugenol: 0.001 to 0.5 g of Permonochlorophenol; 0.001 to 0.3 g of Camphor; 10 to 40 g of Maltitol; 0.01 to 0.1 g of coloring matter; 0.1 to 1 g of appetizing substance and enough quantity of demineralized water to complete 100 g of oral pharmaceutical preparation.