Hydrophilic Coating on Development Member for Sample Analysis

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Solution Overview

Problem

Conventional sample analysis tools experience a decrease in reactivity and reproducibility due to decreased liquid permeability in the development member, leading to incorrect qualitative and quantitative analysis results.

Innovation Solution

A sample analysis tool is designed with a hydrophilic component layer formed on the surface of the development member or plastic base, preventing the adhesion of hydrophobic components and maintaining liquid permeability.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Ease of manufacture

If a plastic base is used to contain the development member, then the structural integrity and ease of manufacture are improved, but the hydrophobic component of the plastic base adheres to the development member, causing liquid permeability to decrease

Engineering Contradiction:
Improveease of manufactureVSAvoidliquid permeability
Core Design Contradiction:
Ease of manufactureVSReliability

Solution Approach 1:

A hydrophilic component layer is introduced as an intermediary between the plastic base and the development member. This layer prevents direct contact between the hydrophobic plastic base and the development member, thereby maintaining liquid permeability while preserving the ease of manufacture provided by the plastic base structure.

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The hydrophilic component layer is applied locally to specific surfaces where contact with the development member occurs. This localized treatment addresses the adhesion problem at critical interfaces without requiring modification of the entire plastic base, thus maintaining manufacturing simplicity while improving liquid permeability reliability.

Inventive Principle:
Principle #3Local quality

2Device complexity

If the development member contacts the plastic base directly, then the device complexity is reduced, but the reactivity and reproducibility of analysis decrease due to decreased liquid permeability

Engineering Contradiction:
Improvedevice complexityVSAvoidreactivity and reproducibility
Core Design Contradiction:
Device complexityVSReliability

Solution Approach 1:

The hydrophilic component layer serves as a mediator that allows the development member to contact the plastic base while preventing harmful adhesion. This maintains the simplicity of the direct contact structure while ensuring proper liquid permeability for reliable and reproducible analysis results.

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The interface between the plastic base and development member is transformed into a composite structure with the hydrophilic component layer. This composite interface combines the structural advantages of the plastic base with the liquid-permeable properties needed for reliable analysis, without significantly increasing device complexity.

Inventive Principle:
Principle #40Composite materials

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The hydrophilic component layer ensures consistent reactivity and reproducibility by preventing the decrease in liquid permeability, thereby improving analysis accuracy.

Implementation Method 1

a hydrophilic component layer disposed on at least a portion of a surface of the plastic base or at least a portion of a surface of the development member

Methodology Applied
Scientific EffectHydrophile-Hydrophobe interaction: Hydrophobe

Data Source

PatentUS9903864B2Sample analysis tool, method for producing sample analysis tool, and method for inhibiting decrease in liquid permeability of development member
Publication Date: 2018.02.27 ARKRAY INC
  • US9903864B2 patent drawing
  • US9903864B2 patent drawing
  • US9903864B2 patent drawing

AI summary

Provide is a sample analysis tool whose reactivity and reproducibility in analysis can be prevented from decreasing. The sample analysis tool 10 of the present invention includes a development member 11 and a plastic base 16, and at least part of the development member 11 is in contact with the plastic base 16. The sample analysis tool 10 further includes a hydrophilic component layer 15, and the hydrophilic component layer 15 is formed on part or the whole of at least one of a surface of the plastic base 16 and a surface of the development member 11. It is particularly preferable that the hydrophilic component layer 15 contains sucrose or N-methyl glucosamine. In the sample analysis tool 10 of the present invention, since the hydrophilic component layer 15 is formed on part or the whole of at least one of the surface of the plastic base 16 and the surface of the development member 11, it is possible to prevent the adhesion of a hydrophobic component(s) derived from the plastic base 16.