Hydroxybiphenyl Benzotriazole Derivatives Block High Energy Light
Find Innovative SolutionsGenerate Solutions
Solution Overview
Problem
Current high energy light blockers, particularly in ophthalmic devices, fail to comprehensively block high energy light across a wide spectrum, including UV and visible light, leading to potential ocular damage, and often have a window in the UV blocking range where protection is reduced.
Innovation Solution
Hydroxybiphenyl benzotriazole derivatives with polymerizable functionality that effectively absorb high energy light across the 200-370 nm range while maintaining transparency in the visible spectrum, providing comprehensive protection against UVA and UVB radiation and high energy visible light.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Object-affected harmful factors
If conventional UV absorbers are used in ophthalmic devices, then some UV protection is achieved, but comprehensive high energy light blocking across 200-400 nm is not achieved and visibility is compromised
Solution Approach 1:
The patent modifies the molecular structure of benzotriazole derivatives by introducing hydroxybiphenyl groups and polymerizable functionality, changing the absorption parameters to block high energy light (200-400 nm) while maintaining visible light transmission (>80%)
Solution Approach 2:
The invention creates composite photoprotective materials by combining hydroxybiphenyl benzotriazole derivatives with polymer matrices, achieving both comprehensive UV/visible light blocking and maintained visibility through optimized composition
2Object-affected harmful factors
If existing benzotriazole compounds are used, then some UV absorption is provided, but a window of reduced protection exists in the UV blocking range
Solution Approach 1:
The patent adjusts the absorption spectrum parameters of benzotriazole derivatives by modifying molecular structure, eliminating the protection window and achieving consistent blocking across the entire UV range (280-380 nm) and into visible light
Solution Approach 2:
The invention enhances specific regions of the absorption spectrum by introducing hydroxybiphenyl groups, creating localized improvements in photostability and absorption efficiency at critical wavelengths while maintaining overall spectral coverage
3Object-affected harmful factors
If polymerizable benzotriazole derivatives are incorporated into ophthalmic devices, then comprehensive high energy light blocking is achieved, but device manufacturing complexity increases
Solution Approach 1:
The patent combines the UV-blocking function with polymerization capability in a single molecular structure, allowing the photoprotective agent to be integrated into the device matrix through standard polymerization processes, thereby simplifying manufacturing despite enhanced functionality
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The hydroxybiphenyl benzotriazole derivatives provide enhanced protection by blocking over 99% of UV radiation between 280-315 nm and 90% of UV radiation between 316-380 nm, while allowing greater than 80% transmission in the visible spectrum, making them suitable for Class I and Class II UV absorbers in ophthalmic applications.
Implementation Method 1
high energy light absorbers with hydroxybiphenyl benzotriazole structures having a high absorption (low transmission) over the wavelength range of at least 200-370 nm
Implementation Method 2
Polymerizable compounds possessing appropriate chromophores, if used as ophthalmic device monomers, can help protect the cornea, as well as the interior cells in the ocular environment, from degradation caused by high energy light
Data Source
Figure 1
Figure 2
Figure 3
AI summary
Described are high energy light blocking compounds and ophthalmic devices containing the compounds. In particular, described are hydroxybiphenyl benzotriazole structures with polymerizable functionality that block high energy light and are visibly transparent. The hydroxybiphenyl benzotriazole structures can be incorporated into ophthalmic devices, such as hydrogel contact lenses, to protect eyes from high energy light radiation.