Hyperhidrosis Composition with Botanical Extracts and Peptides
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Solution Overview
Problem
Current treatments for hyperhidrosis, such as aluminum chloride antiperspirants, prescription drugs, injections, and surgeries, often come with side effects, are invasive, or require cumbersome devices, and do not effectively address excessive sweating without causing emotional and physiological distress.
Innovation Solution
A topical composition combining an antiperspirant, muscle relaxing agents, peptides, and botanical agents, including aluminum zirconium tetrachlorohydrex glycine, gamma amino butyric acid, dipeptide diaminobutyroyl benzylamide diacetate, and plant extracts, applied to a substrate to minimize excessive sweating with reduced side effects.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If high concentrations of aluminum chloride are used to effectively treat hyperhidrosis, then sweating reduction is improved, but skin irritation increases
Solution Approach 1:
The patent combines aluminum chloride with multiple botanical extracts (aloe vera, chamomile, tea tree oil, lavender, eucalyptus) and soothing agents (vitamin E, panthenol) to create a composite formulation that maintains antiperspirant effectiveness while reducing skin irritation through the synergistic calming and anti-inflammatory properties of the botanical components
Solution Approach 2:
The patent modifies the chemical parameters of the antiperspirant by using aluminum chloride in combination with botanical extracts that alter the overall composition's interaction with skin, changing from a harsh single-ingredient approach to a balanced multi-component formulation that achieves effectiveness with reduced irritation
2Reliability
If prescription drugs like oxybutynin and glycopyrrolate are used to reduce hyperhidrosis, then sweating reduction is improved, but side effects such as drowsiness, visual symptoms, and dryness increase
Solution Approach 1:
The patent extracts and uses only the locally effective antiperspirant action at the application site, eliminating the need for systemic absorption that causes drowsiness, visual symptoms, and dryness associated with oral prescription medications
Solution Approach 2:
The botanical extracts serve as intermediaries that provide local soothing and anti-inflammatory effects at the application site, replacing the need for systemic medication and its associated side effects while maintaining treatment effectiveness
3Reliability
If botulinum toxin type A injections are used to disable sweat glands, then sweating reduction is improved, but treatment complexity and invasiveness increase
Solution Approach 1:
The patent replaces the mechanical injection procedure with a topical application system that delivers active ingredients through the skin, eliminating needles and medical monitoring while achieving comparable sweating reduction through the combined action of aluminum chloride and botanical extracts
4Reliability
If endoscopic thoracic sympathectomy surgery is used to treat hyperhidrosis, then sweating reduction is improved, but compensatory sweating and procedure invasiveness increase
Solution Approach 1:
The patent extracts and addresses only the local sweating problem at the application site without interfering with the broader nervous system, thereby avoiding the compensatory sweating effect that occurs when sympathetic nerves are surgically interrupted
Solution Approach 2:
The patent applies treatment locally to affected areas using topical formulation, creating a localized effect that does not disrupt overall autonomic nervous system balance and therefore prevents compensatory sweating in other body regions
5Reliability
If iontophoresis devices are used to combat sweat production, then sweating reduction is improved, but treatment time and device complexity increase
Solution Approach 1:
The patent replaces the complex electrical current delivery system with a simple topical application that allows passive absorption of active ingredients, eliminating the need for time-consuming device sessions while achieving effective sweating reduction through sustained release of antiperspirant and botanical components
Data Source
AI summary
A composition for treatment of hyperhidrosis is provided that contains an effective amount of an antiperspirant. In particular, one embodiment of the composition of the present invention includes an antiperspirant, at least one muscle relaxing agent, at least one peptide, and at least one botanical agent and the composition is applied to a substrate. In another non-limiting illustration, the composition includes from about 0.001 to 50.0 vol % aluminum zirconium tetrachlorohydrex glycine and more preferably 19.0 vol %, glycerin, dipeptide diaminobutyroyl benzylamide diacetate, gamma amino butyric acid, solanum lycopersicum (tomato) extract, gynostemma pentaphyllum extract, panax ginseng root extract, portulaca oleracea extract, butylene glycol, denatured alcohol, and water.