Hyper-osmotic Contact Lens Fluid Absorption Design

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Solution Overview

Problem

Current contact lenses designed to treat corneal edema, such as those described in U.S. Pat. No. 8,096,655, may not effectively manage fluid absorption and refractive properties for individual patient needs, particularly in terms of osmotic gradient and vision modification.

Innovation Solution

A hyper-osmotic contact lens with a central convex disc, peripheral curved portion, annular groove, and apertures is designed to create an osmotic gradient for fluid absorption, using a hyper-osmotic chamber filled with substances like dry hydrogel or glycerol solutions, which can be tailored for refractive properties and stability, allowing for adjustable treatment duration and placement over the cornea or limbus.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Quantity of substance

If a hyper-osmotic contact lens is designed with a microcontainer structure and selective water permeable membrane, then fluid absorption from the cornea is improved, but device complexity increases

Engineering Contradiction:
Improvefluid absorptionVSAvoiddevice complexity
Core Design Contradiction:
Quantity of substanceVSDevice complexity

Solution Approach 1:

The patent extracts the hyper-osmotic chamber as a separate functional component that can be filled with hyper-osmotic substance, allowing the lens to be divided into functional zones: a posterior region with the chamber for fluid absorption and an anterior region for vision correction. This extraction resolves the contradiction by isolating the complex fluid absorption function from the simple vision correction function.

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The patent implements nesting by placing the hyper-osmotic chamber within the contact lens structure, where the chamber is bounded by anterior and posterior walls that are integral parts of the lens. The selective water permeable membrane is positioned within the lens structure to allow water passage while maintaining the chamber's integrity. This nested configuration enables both fluid absorption and vision correction in a single integrated device.

Inventive Principle:
Principle #7Nested doll (Nesting)

2Quantity of substance

If the posterior wall is made of selective water permeable membrane, then water flow from cornea to chamber is improved, but manufacturing precision requirements increase

Engineering Contradiction:
Improvewater flowVSAvoidmanufacturing precision
Core Design Contradiction:
Quantity of substanceVSManufacturing precision

Solution Approach 1:

The patent applies local quality by making only the posterior wall of the hyper-osmotic chamber selective water permeable, while the anterior wall and other lens portions can be made of different materials optimized for vision correction. This localized application of special membrane properties reduces the overall manufacturing complexity while maintaining effective water flow from the cornea into the chamber.

Inventive Principle:
Principle #3Local quality

3Quantity of substance

If the lens is designed to treat corneal edema with osmotic gradient, then dehydration of cornea is improved, but adaptability to individual patient refraction needs decreases

Engineering Contradiction:
Improvedehydration efficiencyVSAvoidrefractive correction adaptability
Core Design Contradiction:
Quantity of substanceVSAdaptability or versatility

Solution Approach 1:

The patent segments the contact lens into distinct functional zones: a posterior region containing the hyper-osmotic chamber for dehydration treatment and an anterior region designed for vision correction. This segmentation allows independent optimization of each function - the posterior chamber maintains high osmotic gradient for effective dehydration while the anterior portion can be customized with different refractive powers to meet individual patient vision needs.

Inventive Principle:
Principle #1Segmentation

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The lens effectively dehydrates the cornea by osmosis, maintaining stability and refractive correction, with the osmotic gradient and aperture design enhancing fluid absorption and surface tension to ensure prolonged treatment efficacy.

Implementation Method 1

The hyper-osmotic contact lens absorbs fluid from an edematous cornea by the force of an osmotic gradient

Methodology Applied
Scientific EffectOsmosis: Osmosis

Implementation Method 2

water from the edematous cornea can flow out of the cornea into the hyper-osmotic chamber by the force of osmosis

Methodology Applied
Scientific EffectOsmosis: Osmosis

Implementation Method 3

The posterior wall, which is the area in which the cornea and the contact lens overlap, is made of a selective water permeable membrane

Methodology Applied
Scientific EffectPermeation: Permeation

Data Source

PatentUS9927632B2Hyper-osmotic eye contact lens
Publication Date: 2018.03.27 EYEYON MEDICAL
  • US9927632B2 patent drawing
  • US9927632B2 patent drawing
  • US9927632B2 patent drawing

AI summary

A hyper-osmotic contact lens including a contact lens including a central convex disc, a peripheral curved portion that extends radially from the disc, an annular groove formed in the disc and one or more apertures formed in the groove.