Hyperoxic Therapy System Using Adaptive Oxygen Dosing
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Solution Overview
Problem
Current hyperoxic therapy lacks clear understanding and consistency in its effectiveness for normal wounds, with unclear conditions under which it produces beneficial outcomes, and often requires hyperbaric pressure, which may not be necessary for all applications.
Innovation Solution
A hyperoxic therapy system that administers hyperoxic gas based on an oxygen dose-response model, adjusting the dosage according to monitored patient parameters, allowing for effective treatment of normal wounds and neurological conditions at normobaric pressure without the need for whole-body chambers.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If hyperbaric oxygen therapy is administered to treat normal wounds, then wound healing is improved, but the treatment requires hyperbaric pressure chambers which increase device complexity and treatment cost
Solution Approach 1:
The patent extracts the essential therapeutic element (hyperoxic gas delivery) from the complex hyperbaric pressure chamber system. By delivering hyperoxic gas at or near atmospheric pressure through localized masks or hoods, the invention removes the need for whole-body hyperbaric chambers while maintaining wound healing effectiveness through targeted oxygen delivery to the treatment area.
Solution Approach 2:
The patent applies local quality by concentrating oxygen delivery at the specific wound site or body region rather than requiring whole-body hyperbaric pressurization. Using localized masks, hoods, or chambers that deliver hyperoxic gas directly to the treatment area allows effective therapy without the complexity of full hyperbaric systems.
2Ease of operation
If fixed-dose hyperoxic therapy is administered, then treatment protocol is simplified, but it cannot adapt to changing patient conditions leading to suboptimal outcomes
Solution Approach 1:
The patent implements dynamic dosing where oxygen concentration and delivery parameters are adjusted in real-time based on patient response and treatment progress. The system transitions from static fixed-dose protocols to adaptive dynamic dosing, modifying treatment parameters according to measured outcomes and patient-specific factors to maintain optimal therapeutic effect throughout the treatment course.
Solution Approach 2:
The patent incorporates feedback mechanisms that monitor patient response to hyperoxic therapy and use this information to adjust subsequent dosing. By measuring treatment outcomes and feeding this data back into the dosing algorithm, the system automatically optimizes oxygen delivery parameters to maintain consistent beneficial outcomes while adapting to changing patient conditions.
3Reliability
If high concentration oxygen is delivered continuously, then therapeutic effect is maximized, but risk of oxygen toxicity increases
Solution Approach 1:
The patent employs periodic or pulsed oxygen delivery rather than continuous high-concentration exposure. By administering hyperoxic gas in controlled intervals or pulses, the system maintains therapeutic oxygen levels during treatment periods while allowing oxygen levels to return to normal during intervals, thereby preventing oxygen toxicity accumulation while preserving treatment efficacy.
Solution Approach 2:
The patent dynamically changes oxygen delivery parameters including concentration, flow rate, and duration based on treatment phase and patient response. The system transitions from fixed high-concentration continuous delivery to variable parameter delivery, adjusting oxygen levels to maintain therapeutic effectiveness while staying below toxicity thresholds through real-time parameter modification.
Data Source
AI summary
The present invention provides systems, methods, and apparatus for applying a hyperoxic therapy delivery system to a patient; administering hyperoxic gas to the patient according to an oxygen dose-response model; and adjusting the administration of the hyperoxic gas to the patient based upon monitored parameters related to a condition of the patient. Numerous additional features are disclosed.


