Dentifrice Formulations with Hypochlorous Acid for Oral Care

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Solution Overview

Problem

Current oral care compositions are inadequate in effectively addressing poor oral health issues such as halitosis, tooth decay, gum disease, and their associated general health problems like heart disease and preterm birth, as they fail to provide comprehensive microbial control and tooth whitening.

Innovation Solution

An oral care composition combining hypochlorite, sodium magnesium silicate, hydrated silica, and a surfactant like sodium coco sulfate, along with a phosphate buffer, which is formulated as a toothpaste or oral rinse to inhibit microbial growth, reduce plaque, and whiten teeth.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If conventional oral care compositions are used, then basic cleaning function is provided, but microbial control and tooth whitening effectiveness are insufficient

Engineering Contradiction:
Improvemicrobial control effectivenessVSAvoidcomposition formulation complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The patent combines multiple active ingredients (hypochlorite, acids, abrasives, surfactants, buffers) into a single integrated oral care composition that simultaneously provides microbial control, cleaning, and whitening functions, resolving the contradiction by merging multiple functions into one formulation

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The oral care composition is designed to perform multiple functions including antimicrobial action, plaque removal, tooth whitening, and cleaning in a single product, thereby improving reliability across multiple oral health parameters without requiring multiple separate products

Inventive Principle:
Principle #6Universality (Multi-functionality)

2Reliability

If hypochlorite is added to oral care composition, then microbial growth inhibition is improved, but formulation stability becomes challenging

Engineering Contradiction:
Improvemicrobial inhibition capabilityVSAvoidformulation stability
Core Design Contradiction:
ReliabilityVSStability of the object's composition

Solution Approach 1:

The patent introduces buffers as intermediary substances that mediate between hypochlorite and other formulation components, controlling pH levels to maintain hypochlorite stability and prevent unwanted reactions, thereby resolving the stability challenge

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The patent carefully controls pH parameters through buffer systems to optimize hypochlorite stability and effectiveness, demonstrating how parameter adjustment resolves the contradiction between microbial inhibition and formulation stability

Inventive Principle:
Principle #35Parameter changes

3Reliability

If multiple active ingredients are combined for comprehensive oral care, then overall oral health improvement is achieved, but manufacturing complexity increases

Engineering Contradiction:
Improvecomprehensive oral health effectivenessVSAvoidmanufacturing simplicity
Core Design Contradiction:
ReliabilityVSEase of manufacture

Solution Approach 1:

The patent performs preliminary formulation work by pre-mixing and stabilizing the multi-ingredient composition during manufacturing, incorporating all necessary components (hypochlorite, acids, abrasives, surfactants, buffers) in predetermined ratios and sequences to simplify the overall manufacturing process while maintaining comprehensive effectiveness

Inventive Principle:
Principle #10Preliminary action

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The composition effectively cleanses and whitens teeth, inhibits microbial growth, reduces plaque and gingivitis, and promotes overall oral health, thereby addressing the broader health implications of poor oral hygiene.

Implementation Method 1

hypochlorous acid, or salts or acids or derivatives thereof... killing or inhibiting the growth or proliferation of microbes

Methodology Applied
Scientific EffectOxidation: Oxidation

Implementation Method 2

an abrasive... the abrasive is hydrated silica... cleansing and whitening teeth

Methodology Applied
Scientific EffectAbrasion: Abrasion

Implementation Method 3

a rheology agent... the rheology agent is sodium magnesium silicate

Methodology Applied
Scientific EffectRheology modification:

Implementation Method 4

a buffer... the buffer is a phosphate buffer... stabilizing the pH

Methodology Applied
Scientific EffectBuffering:

Implementation Method 5

a surfactant... the surfactant is sodium coco sulfate

Methodology Applied
Scientific EffectSurfactant action: Surfactant

Data Source

PatentUS11583481B2Dentifrice formulations and methods of oral care
Publication Date: 2023.02.21 REOXCYN LLC

AI summary

Oral care compositions are disclosed. The compositions include hypochlorous acid in combination with one or more of a rheology agent, an abrasive, a surfactant, a buffer, or an inorganic compound. Methods of using and making the dentifrice compositions are also disclosed.