Hypochlorous Acid Compositions for Heat-Sensitive Device Disinfection

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Solution Overview

Problem

Current disinfection methods for medical devices, particularly heat-sensitive ones, are harsh and reduce their lifespan, while existing sterilization processes are unsuitable, leading to increased medical costs and infection risks due to pathogens.

Innovation Solution

Compositions comprising hypochlorous acid and quaternary compounds, guanide-containing compounds, metallic particles, or metal salts, which provide effective cleaning and disinfection with reduced harshness, extending the lifespan of medical devices and improving disinfection efficacy.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If conventional disinfection processes are used on heat-sensitive medical devices, then disinfection efficacy is achieved, but the medical device lifespan is reduced due to harsh chemical destruction

Engineering Contradiction:

Improvedisinfection efficacyVSAvoidmedical device lifespan

Core Design Contradiction:

ReliabilityVSDuration of action of stationary object

Solution Approach 1:

The patent modifies the chemical parameters of disinfection solutions by using hypochlorous acid at controlled concentrations (50-2000 ppm) combined with specific pH levels (5.0-7.0) and temperatures (20-40°C), creating a less harsh but equally effective disinfection process that preserves medical device integrity while maintaining sterilization capability

Inventive Principle:

Principle #35Parameter changes

Solution Approach 2:

The patent creates composite disinfection formulations by combining hypochlorous acid with quaternary compounds (0.01-5% concentration) and other adjunctive agents, producing a synergistic effect that enhances disinfection efficacy while reducing the harshness and device-damaging potential of individual components

Inventive Principle:

Principle #40Composite materials

2Reliability

If high concentration hypochlorous acid is used for disinfection, then disinfection efficacy is improved, but device integrity is compromised and harshness increases

Engineering Contradiction:

Improvedisinfection efficacyVSAvoidharshness to device

Core Design Contradiction:

ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The patent optimizes hypochlorous acid concentration to a specific range (50-2000 ppm) rather than using high concentrations, and controls pH (5.0-7.0) and temperature (20-40°C) parameters to achieve effective disinfection with minimal harshness and device damage

Inventive Principle:

Principle #35Parameter changes

Solution Approach 2:

The patent introduces quaternary compounds as intermediary agents that work synergistically with hypochlorous acid, allowing lower concentrations of hypochlorous acid to achieve the same disinfection effect, thereby reducing harshness while maintaining efficacy

Inventive Principle:

Principle #24Intermediary (Mediator)

3Reliability

If heat sterilization is used, then complete sterilization is achieved, but heat-sensitive medical devices are damaged

Engineering Contradiction:

Improvesterilization completenessVSAvoiddevice structural integrity

Core Design Contradiction:

ReliabilityVSStrength

Solution Approach 1:

The patent replaces thermal/physical sterilization methods with chemical sterilization using hypochlorous acid-based solutions, eliminating heat exposure that damages heat-sensitive devices while achieving complete sterilization through controlled chemical action

Inventive Principle:

Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The patent changes the sterilization mechanism from thermal energy to chemical energy, using controlled concentrations of hypochlorous acid (50-2000 ppm) at mild temperatures (20-40°C) to achieve sterilization without the structural damage caused by high-temperature autoclaving

Inventive Principle:

Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The compositions offer superior cleaning and disinfection with increased stability and lower hypochlorous acid concentrations, maintaining device integrity and reducing infection risks, thus extending the medical device's lifespan and lowering medical costs.

Implementation Method 1

Compositions comprising hypochlorous acid and quaternary compounds, guanide-containing compounds, metallic particles, or metal salts, which provide effective cleaning and disinfection

Methodology Applied

Scientific EffectDisinfection:

Implementation Method 2

provide superior cleaning and disinfection of a hard surfaces of contamination/biofilm and/or a medical device

Methodology Applied

Scientific EffectCleaning:

Data Source

PatentUS12402628B2Compositions, kits, methods and uses for cleaning, disinfecting, sterilizing and/or treating

Publication Date: 2025.09.02 COLLIDION INC

AI summary

The present specification discloses a composition comprising, consisting essentially of, or consisting of hypochlorous acid or free available chlorine in combination with one or more quaternary compounds or silicon quaternary compounds, one or more guanide-containing compounds, one or more alcohols, one or more metallic particles, one or more metal salts, or any combination thereof. The present specification further discloses a kit comprising, consisting essentially of, or consisting of a one or more containers including a composition disclosed herein or components which make up such compositions as well as methods and uses for such compositions and kits.