External Fixation Pin for Localized Antibiotic Perfusion
Find Innovative SolutionsGenerate Solutions
Solution Overview
Problem
Conventional devices for perfusing antibiotics to bone fracture surgical sites are embedded, making it difficult to adjust antibiotic dose levels and administration intervals, leading to potential overdose or underdose issues due to tissue condition changes.
Innovation Solution
A device for intra medullary antibiotics perfusion (iMAP) that uses an external skeletal fixator with a transfusion tube system, allowing for easy external connection and adjustment of antibiotic dosage based on tissue conditions, featuring a drill attachment for secure fixation and a detachable mechanism for gripping force adjustment.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Quantity of substance
If embedded devices are used for antibiotic perfusion, then antibiotics can be delivered locally to the bone fracture site, but the device cannot be easily adjusted or removed, making dose adjustment difficult
Solution Approach 1:
The device transitions from a static embedded implant to a dynamic external system with adjustable components. The external antibiotic reservoir and perfusion pump allow real-time adjustment of antibiotic delivery parameters (dose, rate, timing) based on tissue condition changes, while the detachable nature enables flexible modification or removal without surgical intervention.
2Quantity of substance
If high dose antibiotics are delivered by intravenous drip, then the bone fracture site receives adequate antibiotic concentration, but other organs are exposed to high dose antibiotics causing adverse effects
Solution Approach 1:
The device implements localized antibiotic delivery by placing the perfusion system directly at the bone fracture site through external fixation pins. The antibiotic reservoir and delivery mechanism are positioned adjacent to the target tissue, enabling high-concentration antibiotic delivery precisely where needed while minimizing systemic circulation and exposure of other organs to therapeutic doses.
3Quantity of substance
If embedded antibiotic delivery devices are used, then local antibiotic delivery is achieved, but the device structure becomes complex and requires surgical embedding and removal
Solution Approach 1:
The device integrates multiple functions into a unified external system: the external fixation pins serve both mechanical stabilization and antibiotic delivery purposes; the antibiotic reservoir combines storage and controlled release functions; the perfusion pump integrates dosing and delivery control. This multi-functional design eliminates the need for separate embedded antibiotic implants, simplifying both installation and removal procedures while maintaining effective local drug delivery.
Data Source
Figure 1(a)~1(c)
Figure 2(a)~2(c)
Figure 3(a)~3(c)
AI summary
[Problem to be solved] A device for intra medullary antibiotics perfusion has a structure which can access easily from the outside and flexibly enables the administration of an antibiotic that is most suitable for a target site according to the circumstances. [Solution] The device for intra medullary antibiotics perfusion (iMAP) 100 is a device for perfusing an antibiotic into the bone fracture surgical site. It comprises a fixation pin (iMAP pin) 110 which comprises a shaft 111, a side face opening 114 formed on the side face of the shaft 111, a base end opening 115 formed in the base end part of the shaft 111, a hollow portion 113 penetrating from the side face opening 113 to the base end opening 115 of the shaft 111, and a screw part 112 formed besides the front end of the shaft 111 and to be screwed into a bone. The fixation pin (iMAP pin) 110 is fixing into a bone externally at a bone fracture site. A transfusion tube connector 120 receives an antibiotic provided from the antibiotic transfusion tube and allows intra medullary antibiotics perfusion from the side face opening 114 of the fixation pin (iMAP pin) 110 via the hollow portion 113.