IGF-1 Acting Cosmetic Composition for Wrinkle Reduction
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Solution Overview
Problem
Current cosmetic products are inadequate in effectively addressing skin aging, as they fail to adequately combat the decline in IGF-1 levels and IGF-1R phosphorylation in skin cells, leading to issues like wrinkles, loss of elasticity, and skin thinness.
Innovation Solution
A cosmetic composition containing a substance that acts on IGF-1 and/or IGF-1R, derived from yeast such as Candida oleophila, is used to increase the expression of IGF-1 mRNA and IGF-1R phosphorylation in skin cells, thereby enhancing skin barrier function and reducing wrinkles.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If conventional cosmetic products are used, then basic skin care functions are maintained, but they fail to effectively combat the decline in IGF-1 levels and IGF-1R phosphorylation, leading to inadequate anti-aging effects
Solution Approach 1:
The patent applies parameter changes by modifying the biochemical parameters of skin cells through the action of IGF-1 and IGF-1R. The cosmetic composition changes the concentration and activity levels of IGF-1 and IGF-1R phosphorylation in skin cells, thereby transforming the physiological state of aging skin to a more youthful state with improved barrier function and reduced wrinkles
Solution Approach 2:
The patent uses IGF-1 and IGF-1R as intermediary substances to mediate the anti-aging effect. These substances act as mediators between the cosmetic composition and the skin cells, transmitting the anti-aging signal by increasing IGF-1 levels and IGF-1R phosphorylation, which then triggers downstream effects including improved skin barrier function and wrinkle reduction
2Reliability
If IGF-1 levels and IGF-1R phosphorylation are increased, then skin barrier function is improved and wrinkles are reduced, but the complexity of the cosmetic composition increases
Solution Approach 1:
The patent applies universality by designing a cosmetic composition that performs multiple anti-aging functions simultaneously. The same composition that increases IGF-1 levels and IGF-1R phosphorylation also improves skin barrier function, reduces wrinkles, and enhances overall skin health, making a single product serve multiple purposes rather than requiring separate treatments for each concern
Data Source
AI summary
The subject matter of the invention is the use, in a cosmetic composition, of an effective amount of at least one substance which acts on insulin-like growth factor IGF-1 and/or on the insulin-like growth factor receptor IGF-1R of skin cells, as a cosmetic active ingredient intended for preventing or combating skin ageing. The invention is also directed towards a cosmetic process for preventing and/or combating skin ageing, comprising the topical application to the skin of a composition comprising at least one substance which acts on IGF-1 and/or IGF-1R of skin cells as a cosmetic active ingredient.