Ileal-Release Carbohydrate Composition for Stable Diabetic Energy

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Solution Overview

Problem

Subjects with metabolic disorders, particularly Type II diabetes, face dangerous spikes in blood sugar levels due to rapid absorption of high glycaemic index carbohydrates, necessitating the avoidance of such products, leading to insufficient energy intake.

Innovation Solution

A composition containing high glycaemic index carbohydrates encapsulated within a gastric-resistant, ileal-sensitive, non-porous carrier for controlled release in the distal ileum, providing sustained energy release and attenuated blood sugar spikes.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Use of energy by moving object

If high GI carbohydrates are consumed, then energy content is high, but blood sugar levels spike rapidly

Engineering Contradiction:
Improveenergy contentVSAvoidblood sugar spikes
Core Design Contradiction:
Use of energy by moving objectVSObject-affected harmful factors

Solution Approach 1:

The patent applies preliminary action by pre-encapsulating high GI carbohydrates in gastric-resistant carriers before consumption. This preliminary encapsulation prevents direct contact between the carbohydrate and the digestive system, thereby preventing rapid absorption and blood sugar spikes while preserving the energy content of the carbohydrate.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The gastric-resistant carrier acts as an intermediary between the high GI carbohydrate and the digestive system. This intermediary protects the carbohydrate from premature digestion and ensures controlled release in the distal ileum, thereby mediating the interaction to avoid harmful blood sugar spikes while maintaining energy availability.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Speed

If simple carbohydrates are absorbed quickly, then energy is released rapidly, but post-prandial blood sugar peaks occur

Engineering Contradiction:
Improveabsorption speedVSAvoidpost-prandial blood sugar peaks
Core Design Contradiction:
SpeedVSObject-affected harmful factors

Solution Approach 1:

The patent applies preliminary action by pre-encapsulating simple carbohydrates in gastric-resistant carriers before consumption. This preliminary encapsulation prevents direct contact between the carbohydrate and the digestive system, thereby preventing rapid absorption and blood sugar spikes while preserving the energy content of the carbohydrate.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The patent applies dynamics by creating a system where the absorption speed of carbohydrates is dynamically controlled through the gastric-resistant carrier. The carrier maintains integrity in the stomach and small intestine, then dynamically releases the carbohydrate in the distal ileum, transforming the static rapid absorption into a controlled dynamic release process.

Inventive Principle:
Principle #15Dynamics

3Object-affected harmful factors

If high energy sugar products are avoided by diabetics, then blood sugar spikes are reduced, but caloric intake becomes insufficient

Engineering Contradiction:
Improveblood sugar regulationVSAvoidcaloric intake
Core Design Contradiction:
Object-affected harmful factorsVSQuantity of substance

Solution Approach 1:

The patent applies segmentation by dividing the carbohydrate delivery process into distinct segments: encapsulation in gastric-resistant carriers, transit through the digestive system, and controlled release in the distal ileum. This segmentation allows diabetics to consume high energy carbohydrates while the segmented delivery system prevents harmful blood sugar spikes, thereby resolving the contradiction between blood sugar regulation and caloric intake.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The patent applies parameter changes by fundamentally altering the release parameters of carbohydrates. Instead of rapid release in the upper digestive tract, the carriers are designed to release carbohydrates in the distal ileum, changing the temporal and spatial parameters of carbohydrate delivery to achieve both blood sugar regulation and adequate caloric intake.

Inventive Principle:
Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The composition effectively regulates post-prandial blood sugar levels, offering sustained energy release and insulin sensitivity, suitable for diabetic subjects, by slowing carbohydrate absorption to the ileum, thus preventing dangerous spikes.

Implementation Method 1

carbohydrate contained within a gastric-resistant, ileal-sensitive, non-porous carrier configured for release of the carbohydrate in the distal ileum

Methodology Applied
Scientific EffectGastric resistance:

Implementation Method 2

carbohydrate contained within a gastric-resistant, ileal-sensitive, non-porous carrier configured for release of the carbohydrate in the distal ileum

Methodology Applied
Scientific EffectIleal sensitivity:

Implementation Method 3

carbohydrate contained within a gastric-resistant, ileal-sensitive, non-porous carrier

Methodology Applied
Scientific EffectPhysical containment: Physical Containment

Data Source

PatentUS12616661B2Composition for type II diabetics and for use in providing sustained energy release over time
Publication Date: 2026.05.05 TEAGASC THE AGRI & FOOD DEVMENT AUTHORITY
  • US12616661B2 patent drawing
  • US12616661B2 patent drawing
  • US12616661B2 patent drawing

AI summary

A composition for use in a method of providing sustained energy release over time in a subject is described. The composition comprises or consists of microparticles comprising high glycaemic index (GI) carbohydrate contained within a gastric-resistant, ileal-sensitive, GLP-1 stimulative, non-porous carrier configured for release of the high GI carbohydrate in the ileum, wherein the composition is administered orally to the subject.