Automated Image Analysis Parameter Optimization

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Solution Overview

Problem

Current methods for setting image analysis parameters in digital image processing are time-consuming, tedious, and require detailed knowledge of the underlying image analysis, making them inefficient for optimizing image analysis operations in high-throughput screening systems.

Innovation Solution

A method and system that collect digital training images, define an objective function to evaluate parameter sets, and use genetic algorithms or exhaustive search methods to determine optimal parameter values, reducing the need for manual expertise and improving usability.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If manual parameter setting methods are used, then expertise in image analysis is required to achieve accurate results, but the process becomes time-consuming and tedious

Engineering Contradiction:
Improveparameter optimization accuracyVSAvoidparameter setting time
Core Design Contradiction:
Measurement precisionVSLoss of time

Solution Approach 1:

The system performs self-optimization of image analysis parameters by automatically evaluating different parameter sets against training images and selecting the optimal configuration without requiring manual expert intervention. The algorithm independently adjusts parameters to maximize performance metrics.

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

The system pre-optimizes parameters using a training set of images before actual analysis. By performing parameter optimization in advance on representative training data, the system prepares optimal parameter sets that can be directly applied to subsequent image analysis tasks, saving time during actual operation.

Inventive Principle:
Principle #10Preliminary action

2Ease of operation

If automated parameter optimization is implemented, then manual labor and expertise requirements are reduced, but system complexity increases

Engineering Contradiction:
ImproveusabilityVSAvoidsystem complexity
Core Design Contradiction:
Ease of operationVSDevice complexity

Solution Approach 1:

The system introduces an automated parameter optimization module as an intermediary between the user and the image analysis engine. This intermediary handles the complex parameter tuning process automatically, shielding users from complexity while delivering optimized results. The module acts as a bridge that translates user requirements into optimal parameter configurations.

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The system implements feedback loops where parameter sets are evaluated based on their performance on training images, and this performance information feeds back into the optimization process. The algorithm uses this feedback to iteratively improve parameter selections, automatically converging on optimal settings without human intervention.

Inventive Principle:
Principle #23Feedback

3Measurement precision

If exhaustive search methods are used to find optimal parameters, then measurement precision is improved, but productivity decreases due to computational intensity

Engineering Contradiction:
Improveparameter optimization accuracyVSAvoidprocessing speed
Core Design Contradiction:
Measurement precisionVSProductivity

Solution Approach 1:

The system applies partial exhaustive search by evaluating a strategically selected subset of parameter combinations rather than all possible combinations. By focusing computational resources on the most promising parameter ranges and using heuristics to guide the search, the system achieves near-optimal results with significantly reduced computational overhead.

Inventive Principle:
Principle #16Partial or excessive action

Solution Approach 2:

The system performs preliminary parameter narrowing before the main optimization process. By pre-processing training images and identifying relevant parameter ranges based on image characteristics, the system reduces the search space for subsequent optimization, balancing thoroughness with computational efficiency.

Inventive Principle:
Principle #10Preliminary action

Data Source

PatentUS7818130B2Automated method and system for setting image analysis parameters to control image analysis operations
Publication Date: 2010.10.19 CELLOMICS INC
  • US7818130B2 patent drawing
  • US7818130B2 patent drawing
  • US7818130B2 patent drawing

AI summary

A method and system for setting image analysis parameters to control image analysis operations. The method and system include collecting set of digital training images including a set of states for the set of digital training images. An objective function is defined to determine a relative quality of plural different parameter sets used for digital image analysis. Values for the plural different parameter sets that maximize (or minimize) the objective function are determined. The method and system increases a usability of high content screening technologies by reducing a required level of expertise required to configure digital image processing.