Overlaying High-Magnification Images on Low-Resolution Views

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Solution Overview

Problem

Investigators face a tedious and error-prone process when reviewing sample images at low magnification, identifying areas of interest, and inspecting them at higher magnification, as they often involve comparing separate low- and high-magnification images from different files.

Innovation Solution

The method involves collecting images at two levels of magnification and overlaying the higher-magnification images onto the lower-magnification images, allowing for precise alignment and display of regions of interest within their original positional context, using imaging devices and processors to facilitate this process.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If investigators compare low- and high-magnification images from separate computer files, then they can inspect areas of interest at higher magnification, but the process becomes tedious, time-consuming, and error-prone

Engineering Contradiction:
Improveinspection precisionVSAvoidreview time
Core Design Contradiction:
Measurement precisionVSLoss of time

Solution Approach 1:

The patent combines low-magnification and high-magnification images into a single composite display, where the high-magnification image is overlaid on the corresponding region of the low-magnification image. This merging eliminates the need to switch between separate files and manually track positions, directly reducing review time while maintaining inspection precision.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The patent introduces a composite image as an intermediary representation that bridges low- and high-magnification views. This composite image serves as a mediator that preserves spatial context and allows investigators to see both magnification levels simultaneously without the tedious process of comparing separate files.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Loss of information

If investigators manually track the origin of magnified areas, then they can maintain spatial context, but the process becomes error-prone and time-consuming

Engineering Contradiction:
Improvespatial contextVSAvoidtracking accuracy
Core Design Contradiction:
Loss of informationVSReliability

Solution Approach 1:

By merging the high-magnification image with the low-magnification image in a composite display, the patent automatically preserves spatial context through visual overlay. The high-magnification region is positioned exactly where it originates in the low-magnification image, eliminating manual tracking and its associated errors.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The patent creates a visual copy of the high-magnification image and places it directly over the corresponding region in the low-magnification image. This copying approach automatically maintains spatial relationships without requiring manual intervention, thereby improving reliability while preserving spatial context.

Inventive Principle:
Principle #26Copying

3Adaptability or versatility

If investigators use separate files for low- and high-magnification images, then they can achieve different magnification levels, but the process lacks integration and efficiency

Engineering Contradiction:
Improvemagnification flexibilityVSAvoidanalysis efficiency
Core Design Contradiction:
Adaptability or versatilityVSProductivity

Solution Approach 1:

The patent merges multiple magnification levels into a single integrated composite image display. This allows investigators to maintain magnification flexibility by viewing different levels simultaneously while dramatically improving analysis efficiency through the unified interface that eliminates file-switching and manual coordination.

Inventive Principle:
Principle #5Merging (Combining)

Data Source

PatentUS11416997B2Systems, methods, and apparatuses for image capture and display
Publication Date: 2022.08.16 LIFE TECHNOLOGIES CORP
  • US11416997B2 patent drawing
  • US11416997B2 patent drawing
  • US11416997B2 patent drawing

AI summary

Provided are systems and methods that allow a user to capture images at low- and high-level magnification and then overlay the high-level magnification images on the low-level magnification image to ease review of the images. The high-level magnification images may be overlaid on the low-level magnification image based at least in part on the portion of the low-level magnification image from which the high-level image was originated.