Imaging Device Wavelength Separation for Fluorescence Detection

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Solution Overview

Problem

Current endoscope systems face challenges in simultaneously capturing high-quality visible light and infrared fluorescence images, particularly in distinguishing between blue and green fluorescence, which limits their ability to accurately detect lesions like cancer.

Innovation Solution

The proposed imaging device employs a light splitting unit that separates infrared light from red, green, and blue light, using specific filters and dichroic prisms to isolate and process each wavelength range, allowing for the generation of distinct signals for visible light and infrared images, and further separates blue and green light when necessary, enabling precise fluorescence detection.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Device complexity

If a single image sensor is used to capture both visible light and infrared fluorescence, then device complexity is reduced, but measurement precision deteriorates because the sensor cannot simultaneously distinguish between different wavelength ranges with high accuracy

Engineering Contradiction:
Improvenumber of image sensorsVSAvoidwavelength discrimination accuracy
Core Design Contradiction:
Device complexityVSMeasurement precision

Solution Approach 1:

The patent divides the imaging function into multiple specialized image sensors, each optimized for specific wavelength ranges. The first image sensor captures visible light (blue, green, red channels), while the second image sensor captures infrared fluorescence. This segmentation allows each sensor to be optimized for its specific function, achieving high measurement precision without requiring a single complex sensor to handle all wavelengths.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The patent introduces a dichroic mirror as an intermediary optical element that separates the visible light and infrared fluorescence paths. The dichroic mirror reflects infrared wavelengths to the second image sensor while transmitting visible wavelengths to the first image sensor, enabling simultaneous high-precision capture of both wavelength ranges without direct competition for the same sensor resources.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Device complexity

If blue and green fluorescence are not separated, then device complexity is reduced, but measurement precision deteriorates because blue and green fluorescence cannot be distinguished

Engineering Contradiction:
Improvelight separation mechanismVSAvoidfluorescence wavelength distinction
Core Design Contradiction:
Device complexityVSMeasurement precision

Solution Approach 1:

The patent applies local quality by assigning different spectral sensitivity characteristics to different regions of the first image sensor. The blue light reception region and green light reception region are spatially separated and optimized for their respective wavelength ranges, allowing the system to distinguish between blue and green fluorescence with high precision while using a single image sensor unit.

Inventive Principle:
Principle #3Local quality

Solution Approach 2:

The patent employs a switchable or tunable optical filter system that can dynamically adjust which wavelength ranges are transmitted to which sensor regions. This dynamic capability allows the system to adaptively separate blue and green fluorescence when needed, while maintaining operational simplicity when full separation is not required.

Inventive Principle:
Principle #15Dynamics

3Device complexity

If excitation light is not filtered out, then device complexity is reduced, but measurement precision deteriorates because excitation light interferes with fluorescence detection

Engineering Contradiction:
Improvefiltering systemVSAvoidfluorescence signal clarity
Core Design Contradiction:
Device complexityVSMeasurement precision

Solution Approach 1:

The patent extracts and removes the excitation light component from the optical path before it reaches the image sensors. An excitation light cut filter is positioned in the optical path to selectively block excitation wavelengths while transmitting fluorescence wavelengths. This extraction of the harmful excitation light component prevents interference with fluorescence detection, achieving high measurement precision without requiring complex filtering systems.

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The patent converts the potential harm of excitation light interference into a benefit by using the excitation light's specific wavelength characteristics to design targeted filtering. The excitation light cut filter is engineered to precisely block excitation wavelengths while transmitting the longer wavelength fluorescence, transforming what would be a harmful interference into a well-defined optical separation that enhances detection precision.

Inventive Principle:
Principle #22Blessing in disguise (Convert harm into benefit)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This solution enables the simultaneous acquisition of high-quality visible light and infrared fluorescence images, improving the detection of lesions by accurately distinguishing between different fluorescence wavelengths, thus enhancing diagnostic capabilities.

Implementation Method 1

a light splitting unit that splits first light from a subject into second light and third light. The first light includes the second light and the third light. The second light includes infrared light, and at least one of a group consisting of green light and blue light

Methodology Applied
Scientific EffectLight splitting / Wavelength separation: Dispersion (of waves)

Implementation Method 2

The first light reception region is configured to generate at least one of the group consisting of a B signal according to the blue light and a G signal according to the green light

Methodology Applied
Scientific EffectPhotoelectric detection: Photoelectric Effect

Implementation Method 3

The infrared light transmitted through the first light reception region is incident on the second light reception region. The second light reception region is configured to generate an IR signal according to the infrared light

Methodology Applied
Scientific EffectInfrared detection: Infrared Radiation

Implementation Method 4

a dichroic prism that separates visible light into red, green, and blue components

Methodology Applied
Scientific EffectDichroic reflection: Dichroic Filter

Data Source

PatentUS10516836B2Imaging device
Publication Date: 2019.12.24 OLYMPUS CORPORATION(JP)
  • US10516836B2 patent drawing
  • US10516836B2 patent drawing
  • US10516836B2 patent drawing

AI summary

An imaging device includes a light splitting unit which splits first light from a subject into second light and third light, first and second imaging units, and an arithmetic unit. The first light includes the second light having infrared light and at least one of green light and blue light, and the third light having red light or the green light. The first imaging unit includes a first and a second light reception regions. The first light reception region generates at least one of the group consisting of a B signal according to the blue light and a G signal according to the green light. The second light reception region generates an IR signal according to the infrared light. The arithmetic unit generates a visible light image signal from the R signal, the G signal, and the B signal and generates an infrared light image signal from the IR signal.