Imidazole Herbicidal Compounds for Selective Weed Control

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Solution Overview

Problem

Existing herbicides lack effective and selective control of weeds in crops, particularly in plants that are inherently tolerant or genetically modified to resist other herbicides.

Innovation Solution

Development of novel herbicidal imidazole compounds, formulated into compositions with agronomically acceptable salts and adjuvants, providing enhanced selectivity and efficacy against weeds while minimizing impact on crop plants.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If existing herbicides are used to control weeds, then weed control is achieved, but selectivity and efficacy are insufficient particularly against tolerant crops and genetically modified plants

Engineering Contradiction:
Improveweed control efficacyVSAvoidimpact on crop plants
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The patent modifies the chemical structure of imidazole compounds by changing parameters such as substituting the phenyl group at position Q with 5-membered heteroaryl groups (pyridine, pyrimidine, triazine, oxazole, thiazole), altering substituents at positions R1-R4, and adjusting molecular weight and lipophilicity. These parameter changes create new chemical entities with improved selectivity and efficacy against weeds while reducing harm to tolerant crops and genetically modified plants.

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent creates composite herbicidal compositions by combining the novel imidazole compounds with formulation adjuvants and other agronomically acceptable substances. These composite formulations enhance the overall performance, selectivity, and efficacy of the herbicide while minimizing negative impacts on crop plants, achieving superior weed control compared to single-component herbicides.

Inventive Principle:
Principle #40Composite materials

2Reliability

If herbicidal compositions are developed with enhanced selectivity, then weed control in tolerant crops is improved, but formulation complexity increases

Engineering Contradiction:
ImproveselectivityVSAvoidformulation complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The patent optimizes formulation parameters such as concentration levels, pH, viscosity, and compatibility with crop plants. By carefully adjusting these parameters in the herbicidal compositions, the patent achieves enhanced selectivity and efficacy while maintaining formulation stability and ease of application, avoiding excessive complexity.

Inventive Principle:
Principle #35Parameter changes

Data Source

PatentUS20250243189A1Herbicidal imidazole-containing compounds
Publication Date: 2025.07.31 SYNGENTA CROP PROTECITON AG
  • US20250243189A1 patent drawing
  • US20250243189A1 patent drawing
  • US20250243189A1 patent drawing

AI summary

The present invention relates to compounds of Formula (I) or an agronomically acceptable salt of said compounds wherein A, Q, R1, R2, R4 and m are as defined herein. The invention further relates to herbicidal compositions which comprise a compound of Formula (I) and to the use of compounds of Formula (I) for controlling weeds, in particular in crops of useful plants.