Implant Heterogeneous Surface Biocompatibility via Masking

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Solution Overview

Problem

Current implants lack flexibility in tailoring their interaction with biological tissue, as they often have homogeneous surfaces with uniform biocompatibility, which limits their adaptability and long-term effectiveness, especially when interacting with different types of biological systems.

Innovation Solution

An implant with a heterogeneous surface structure comprising a ground surface and deliberately distributed delimited regions, where the properties of the ground surface and the delimited regions differ in biocompatibility, allowing for tailored interaction with specific biological systems. This is achieved through methods such as applying bioactive materials like hydroxyapatite using masking units and surface topographical modifications like patterning or texturing.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Adaptability or versatility

If a homogeneous surface with uniform biocompatibility is used, then the implant structure is simple and easy to manufacture, but the adaptability to different biological systems is limited

Engineering Contradiction:
Improveadaptability to different biological systemsVSAvoidsurface structure complexity
Core Design Contradiction:
Adaptability or versatilityVSDevice complexity

Solution Approach 1:

The implant surface is divided into multiple regions with different biocompatibility properties. A first region has a first biocompatibility level while a second region has a second biocompatibility level, allowing the implant to interact differently with various biological systems at different locations. This local differentiation resolves the contradiction by providing adaptability without requiring complete surface replacement.

Inventive Principle:
Principle #3Local quality

Solution Approach 2:

The surface is segmented into distinct functional zones including a first region with specific biocompatibility characteristics and a second region with different characteristics. This segmentation enables the implant to address multiple biological requirements simultaneously, improving versatility while maintaining a manageable structural complexity through defined regional boundaries.

Inventive Principle:
Principle #1Segmentation

2Reliability

If a homogeneous surface is used, then the manufacturing process is simple, but the tissue integration and mechanical stability are insufficient

Engineering Contradiction:
Improvetissue integration and mechanical stabilityVSAvoidmanufacturing process complexity
Core Design Contradiction:
ReliabilityVSEase of manufacture

Solution Approach 1:

Different surface regions are engineered with specific properties optimized for their functional requirements. The first region provides enhanced tissue integration while the second region ensures mechanical stability, allowing each area to perform its specialized function effectively without complicating the overall manufacturing process beyond regional treatment steps.

Inventive Principle:
Principle #3Local quality

3Loss of time

If uniform biocompatibility is applied across the surface, then the implant is easy to produce, but the healing time is prolonged

Engineering Contradiction:
Improvehealing timeVSAvoidsurface property variation
Core Design Contradiction:
Loss of timeVSDevice complexity

Solution Approach 1:

The surface is differentiated into regions with optimized biocompatibility properties that accelerate specific healing processes. The first region promotes faster tissue integration while the second region maintains structural integrity, collectively reducing overall healing time without requiring complex multi-material construction.

Inventive Principle:
Principle #3Local quality

4Adaptability or versatility

If different materials are used for different surface parts, then the biocompatibility can be tailored, but the manufacturing complexity increases

Engineering Contradiction:
Improvebiocompatibility tailoringVSAvoidmanufacturing flexibility
Core Design Contradiction:
Adaptability or versatilityVSEase of manufacture

Solution Approach 1:

The implant employs regions with different biocompatibility characteristics achieved through controlled material deposition or surface treatment rather than assembling multiple materials. This approach enables biocompatibility tailoring while maintaining manufacturing flexibility by applying treatments to specific zones of a base implant structure.

Inventive Principle:
Principle #3Local quality

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The heterogeneous surface structure enhances the implant's biocompatibility and bioactivity, facilitating deeper tissue integration and mechanical stability, while avoiding the drawbacks of uniform surfaces, such as poor elastic deformation and prolonged healing times.

Implementation Method 1

applying, from the outside of the masking unit, said one or several delimited regions in the form of deposits such that the apertures of the masking unit define said second part of the surface

Methodology Applied
Scientific EffectPhysical Vapour Deposition: Physical Vapour Deposition

Implementation Method 2

a topographical modification of the implant, for example by patterning or raising/texturing the surface to improve the contact between the implant and the tissue

Methodology Applied
Scientific EffectSurface texturing/patterning:

Data Source

PatentUS8377106B2Implant and an implant member
Publication Date: 2013.02.19 INTEGRUM
  • US8377106B2 patent drawing
  • US8377106B2 patent drawing
  • US8377106B2 patent drawing

AI summary

An implant and an implant member for attaching to living biological tissue of a human being or an animal. The implant has an outer surface comprising a first part and a second part which have different properties with regard to the biocompatibility of each part with biological tissue. The implant includes at least one surface portion comprising a ground surface making up the first part and one or several delimited regions making up said second part. A method for producing the implant, where a perforated masking unit is applied onto the implant, and a masking unit for the method.