Implant Laser Genotype Pulse Modulation for Bone Fusion

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Solution Overview

Problem

Current material substrates, such as skeletal implants, require external interventions and lack customization, leading to invasive procedures and inefficiencies in tissue growth and bone fusion due to inadequate integration and maintenance requirements.

Innovation Solution

The development of material substrates with built-in electromechanical properties, utilizing laser genotype pulse modulation and ferroelectric, piezoelectric, and pyroelectric activation to create complex architectures that respond to physiological forces and stimuli, enabling site-selective phase conversion and biofeedback for enhanced tissue attachment and bone growth.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If external interventions are used to enhance tissue growth and bone fusion, then tissue growth and bone fusion can be facilitated, but invasive procedures and additional surgery are required

Engineering Contradiction:
Improvetissue growth and bone fusionVSAvoidinvasive procedures and additional surgery
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The implant is designed with built-in electromechanical properties that enable it to self-stimulate tissue growth and bone fusion without requiring external interventions. The implant autonomously generates electrical signals through mechanical loading, which then stimulate cellular activity and promote integration, eliminating the need for additional surgical procedures or external power sources.

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

The patent replaces external mechanical stimulation devices and power sources with an intrinsic electromechanical system embedded in the implant. The implant converts mechanical forces from normal physiological loading into electrical signals that stimulate tissue growth, substituting complex external mechanical systems with a simpler self-contained electromechanical mechanism.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

2Strength

If passive structural systems are used for implants, then mechanical integrity and biocompatibility can be achieved, but customization and genetic design are limited

Engineering Contradiction:
Improvemechanical integrity and biocompatibilityVSAvoidcustomization and genetic design
Core Design Contradiction:
StrengthVSAdaptability or versatility

Solution Approach 1:

The implant transitions from a static passive structure to a dynamic active system that responds to mechanical loading. The electromechanical properties enable the implant to adapt its electrical signal output based on the magnitude and frequency of applied forces, allowing customization of stimulation patterns to match specific patient needs and physiological conditions.

Inventive Principle:
Principle #15Dynamics

Solution Approach 2:

The implant incorporates spatially varying electromechanical properties and surface characteristics that can be customized for different regions. This allows different areas of the implant to have tailored properties for optimizing both mechanical performance and biological response, enabling localized customization without compromising overall structural integrity.

Inventive Principle:
Principle #3Local quality

3Reliability

If mechanical and chemical modalities are used to facilitate integration, then surface structure and roughness can be improved, but frequent maintenance and external power sources are required

Engineering Contradiction:
Improveintegration into the bodyVSAvoidexternal power sources and frequent maintenance
Core Design Contradiction:
ReliabilityVSUse of energy by stationary object

Solution Approach 1:

The patent replaces external power sources and chemical treatment systems with a mechanically-driven electromechanical system. The implant harvests energy from normal physiological mechanical loading to generate electrical signals, eliminating the need for batteries, external power connections, or frequent maintenance of external equipment.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The implant autonomously generates the electrical signals needed for tissue stimulation through normal physiological loading. The system self-regulates its operation based on the mechanical forces it experiences, requiring no external control, power input, or maintenance, thereby eliminating the energy and maintenance burden of external systems.

Inventive Principle:
Principle #25Self-service

4Adaptability or versatility

If built-in electromechanical properties are integrated into implants, then customization and tissue growth guidance can be enhanced, but device complexity increases

Engineering Contradiction:
Improvecustomization and tissue growth guidanceVSAvoidbuilt-in electromechanical properties
Core Design Contradiction:
Adaptability or versatilityVSDevice complexity

Solution Approach 1:

The implant utilizes variations in material composition, microstructure, and surface properties to achieve different electromechanical responses without adding complex mechanical or electronic components. By adjusting parameters such as piezoelectric coefficient, mechanical stiffness, and surface topography, the implant can be customized for different applications while maintaining a relatively simple overall structure.

Inventive Principle:
Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This approach facilitates improved integration and customization of implants, reducing the need for external interventions by guiding cellular activity and enhancing bone fusion through electromechanical pathways, resulting in more effective and efficient tissue growth and implant stability.

Implementation Method 1

a laser is administered in a discrete and pre-defined packet of photons synchronized with the pattern and biogeometry to create a tapestry or mosaic of material states on the material substrate with different phases, compositions, and functionalities

Methodology Applied
Scientific EffectLaser ablation: Laser Ablation

Implementation Method 2

site-selective phase conversion and ferroelectric, piezoelectric, and pyroelectric activation

Methodology Applied
Scientific EffectPhase conversion: Phase Change

Implementation Method 3

ferroelectric, piezoelectric, and pyroelectric activation

Methodology Applied
Scientific EffectFerroelectric effect:

Implementation Method 4

ferroelectric, piezoelectric, and pyroelectric activation

Methodology Applied
Scientific EffectPiezoelectric effect: Piezoelectric Effect

Data Source

PatentUS10613513B2Systems and methods for modifying material substrates
Publication Date: 2020.04.07 AEROSPACE CORP
  • US10613513B2 patent drawing
  • US10613513B2 patent drawing
  • US10613513B2 patent drawing

AI summary

A system includes a computing device that generates at least one process script for the modification to a material substrate and at least one pattern script that corresponds to the process script. The computing device also merges the process script with the pattern script and generates a plurality of command signals that are based on the merged process and pattern scripts. An energy source generates a plurality of light beams based on the generated command signal(s). At least one modulating component modulates the generated light beams based on generated command signal(s). A waveform apparatus generates at least one waveform signal to customize the generated light beams based on the generated command signal(s). A motion control apparatus controls at least one parameter of the light beams based on the generated command signal(s).