Implantable CSF Valve With Gravity-Shifted Opening Pressure

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Solution Overview

Problem

Existing shunt systems for treating normal pressure hydrocephalus (NPH) face challenges in setting the response threshold, leading to inadequate treatment outcomes or hydrostatic overdrainage, as the mean pressure is not consistently elevated, and patients experience fluctuating pressure increases, particularly during sleep and when lying down.

Innovation Solution

An implantable valve with a unique design that closes in an upright position and opens at a lower pressure in a lying position, utilizing gravity and spring force to prevent overdrainage, featuring a valve body assembly that seals against two seats, ensuring drainage only at specific pressure differentials.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Adaptability or versatility

If a fixed response pressure valve is used, then the valve structure is simple, but it cannot adapt to fluctuating pressure conditions in NPH patients, leading to inadequate treatment or overdrainage

Engineering Contradiction:
Improveadaptability to pressure fluctuationsVSAvoidvalve structure complexity
Core Design Contradiction:
Adaptability or versatilityVSDevice complexity

Solution Approach 1:

The valve incorporates a movable valve body that can dynamically change its position between two valve seats based on pressure differential and gravitational forces. This dynamic mechanism allows the valve to automatically adjust its response pressure according to body position (upright vs. lying), enabling adaptation to fluctuating pressure conditions without requiring complex external control systems

Inventive Principle:
Principle #15Dynamics

Solution Approach 2:

The valve body is designed with specific weight characteristics and is acted upon by gravitational force that counterbalances the spring force in upright positions. This gravitational counterweight effect creates position-dependent pressure thresholds, where the valve responds to different pressure differentials when upright versus lying, providing adaptability through passive gravitational compensation

Inventive Principle:
Principle #8Anti-weight (Counterweight)

2Object-affected harmful factors

If the response threshold is set high to prevent overdrainage in upright position, then overdrainage is reduced, but treatment becomes inadequate when patients are lying down or sleeping

Engineering Contradiction:
Improveoverdrainage preventionVSAvoiddrainage efficiency
Core Design Contradiction:
Object-affected harmful factorsVSProductivity

Solution Approach 1:

The valve dynamically adjusts its operational characteristics based on body position. In upright positions, the gravitational force on the valve body assists the spring force to maintain a higher effective response threshold, preventing overdrainage. In lying positions, gravity acts perpendicular to the valve axis, reducing its effect and allowing drainage at lower pressure differentials, thus ensuring adequate treatment during sleep

Inventive Principle:
Principle #15Dynamics

Solution Approach 2:

The valve effectively changes its response pressure parameter according to orientation. The same physical valve structure exhibits different functional thresholds: a higher effective threshold when upright and a lower effective threshold when lying down, allowing it to prevent overdrainage while maintaining treatment efficacy without requiring multiple valves or complex control mechanisms

Inventive Principle:
Principle #35Parameter changes

3Productivity

If gravity-compensated systems are used to adapt response pressure to body position, then treatment effectiveness improves, but the valve becomes more complex and requires precise adaptation within narrow limits

Engineering Contradiction:
Improvetreatment effectivenessVSAvoidgravity compensation mechanism
Core Design Contradiction:
ProductivityVSDevice complexity

Solution Approach 1:

The valve performs self-adjustment based on its own weight and the gravitational field. The valve body's mass and geometry are designed so that gravity automatically provides the compensation needed for different positions. No external sensors, actuators, or control systems are required - the valve serves itself by utilizing the natural gravitational force acting on its own structure

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

Gravitational force acts as an intermediary between the valve's physical structure and its functional response. The gravity force mediates the interaction between the valve body and spring, creating position-dependent force balance that automatically adjusts the valve's operational characteristics without requiring complex control mechanisms

Inventive Principle:
Principle #24Intermediary (Mediator)

4Productivity

If the valve opens at low pressure to ensure adequate drainage in lying position, then treatment effectiveness improves, but hydrostatic overdrainage occurs when patients stand upright

Engineering Contradiction:
Improvedrainage adequacyVSAvoidhydrostatic overdrainage
Core Design Contradiction:
ProductivityVSObject-affected harmful factors

Solution Approach 1:

The valve body's weight acts as a counterbalancing force that prevents overdrainage in upright positions. When the patient is upright, gravity pulls the valve body in a direction that increases the force required to open the valve, effectively raising the response threshold. This gravitational counterweight effect automatically prevents hydrostatic overdrainage without requiring active control

Inventive Principle:
Principle #8Anti-weight (Counterweight)

Solution Approach 2:

The valve dynamically responds to changes in gravitational direction relative to the valve axis. The movable valve body adjusts its equilibrium position based on the vector sum of spring force and gravitational force, creating a dynamic system that automatically prevents overdrainage in upright positions while allowing adequate drainage in lying positions

Inventive Principle:
Principle #15Dynamics

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The valve effectively prevents unphysiologically high drainage volumes, reducing the risk of overdrainage by maintaining slight pressure gradients and ensuring efficient drainage, particularly effective in preventing overdrainage during changes in body position.

Implementation Method 1

a spring device arranged in the interior space which exerts a spring force on the valve body assembly in the direction of the first valve seat

Methodology Applied
Scientific EffectSpring force: Spring

Implementation Method 2

the valve body assembly is configured to seal against the first valve seat to close a flow connection between the inlet and the interior space of the valve housing

Methodology Applied
Scientific EffectSealing:

Implementation Method 3

the weight force of the valve body assembly is greater than the spring force when the valve housing is in a vertical position

Methodology Applied
Scientific EffectGravity: Gravitation

Data Source

PatentEP3902592B1Valve for permanent implantation, in particular for treatment of normal pressure hydrocephalus
Publication Date: 2026.01.28 UNIVERSITY OF BERN
  • EP3902592B1 patent drawingFigure 1
  • EP3902592B1 patent drawingFigure 2
  • EP3902592B1 patent drawingFigure 3~4

AI summary

The invention relates to an implantable valve (1) for a drainage device for draining cerebrospinal fluid, having: a valve housing (10) which has an inlet (2), an outlet (3) and an interior (4); a valve body arrangement (600) movably disposed in the interior (4); a first valve seat (5), the valve body arrangement (600) being designed to bear on the first valve seat (5) so as to close a flow connection between the inlet (2) and the interior (4) of the valve housing (10); a second valve seat (7) which lies opposite the first valve seat (5), the valve body arrangement (600) being designed to bear on the second valve seat (7) so as to close a flow connection between the outlet (3) and the interior (4) of the valve housing (10); and a spring mechanism (800) which is disposed in the interior (4) and exerts a spring force on the valve body arrangement (600) in the direction of the first valve seat (5).