Implantable Neuromodulation Device for Obstetric Disorders

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Solution Overview

Problem

Women's health disorders, such as obstetric and gynecological conditions other than urinary incontinence, have historically received less attention and existing treatments are inadequate, with significant economic and quality-of-life impacts.

Innovation Solution

Development of neuromodulatory devices and systems that include therapy delivery devices with electrodes and power sources configured for implantation in reproductive systems to deliver electrical signals to autonomic nervous system nerve targets, potentially combined with closed-loop systems for automatic modulation of these signals based on detected physiological parameters.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If existing treatments for obstetric and gynecological disorders are used, then treatment coverage is limited, but development costs and device complexity increase

Engineering Contradiction:
Improvetreatment effectivenessVSAvoiddevice complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The therapy delivery device is designed to treat multiple obstetric and gynecological disorders (preterm labor, menstrual disorders, sexual dysfunction, pelvic pain, endometriosis, fibroids) through a single multi-functional platform, eliminating the need for separate devices for each condition while maintaining targeted effectiveness for each specific disorder

Inventive Principle:
Principle #6Universality (Multi-functionality)

Solution Approach 2:

The device uses electrical signals as an intermediary mechanism to modulate autonomic nervous system activity, which in turn regulates various reproductive system functions. This intermediary approach allows treatment of diverse conditions through a common physiological pathway rather than requiring condition-specific mechanical interventions

Inventive Principle:
Principle #24Intermediary (Mediator)

2Adaptability or versatility

If neuromodulatory devices with multiple components are developed, then treatment capability improves, but manufacturing complexity increases

Engineering Contradiction:
Improvetreatment versatilityVSAvoidmanufacturing ease
Core Design Contradiction:
Adaptability or versatilityVSEase of manufacture

Solution Approach 1:

The patent combines multiple functional components (electrodes for electrical signal delivery, power source, housing configured for implantation in reproductive systems) into a single integrated therapy delivery device. This merging reduces the number of separate manufacturing processes and assembly steps compared to using multiple separate devices

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The device is designed as a universal platform that can treat multiple obstetric and gynecological conditions through standardized components, allowing mass production of a single device type rather than custom manufacturing for each condition

Inventive Principle:
Principle #6Universality (Multi-functionality)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

These devices and systems effectively treat obstetric and gynecological disorders by modulating autonomic nervous system activity, providing a targeted and potentially more effective approach than existing treatments.

Implementation Method 1

The at least one electrode can be connected to the housing and be configured to deliver an electrical signal to an autonomic nervous system (ANS) nerve target

Methodology Applied
Scientific EffectElectrical signal delivery: Conduction (electrical)

Data Source

PatentUS10016599B2Devices, systems, and methods for treating obstetric and gynecological disorders
Publication Date: 2018.07.10 OHIO STATE INNOVATION FOUND
  • US10016599B2 patent drawing
  • US10016599B2 patent drawing
  • US10016599B2 patent drawing

AI summary

One aspect of the present disclosure relates to a therapy delivery device for treating an obstetric or gynecological disorder other than urinary incontinence in a subject. The therapy delivery device can include a housing, at least one electrode, and a power source. The housing can be configured for implantation in a reproductive system of the subject. The at least one electrode can be connected to the housing and be configured to deliver an electrical signal to an autonomic nervous system nerve target. The power source can be in electrical communication with the at least one electrode.